Variability in symptoms hinders diagnosis. The gold standard for diagnosis is MRI, but clinical suspicion optimizes imaging test diagnosis. Segmental resection should be indicated in the majority of the cases.

ORIGINAL RESEARCH ARTICLE to 40% (5). Thus, sciatica and endometriosis are frequent pathologies and it is not uncommon for them to occur simultaneously. Endometriosis as the cause of sciatica by direct involvement of the sciatic nerve is extremely rare. This condition was first described by Denton and Sherrill (6). In relation to this issue, the most important thing is that neuropathy can occur over time, and because diagnosis is usually delayed for years, serious and often irreversible consequences that affect the quality of life of patients happen. We report our experience in the diagnosis, management and treatment of two cases of endometriosis with histologic confirmation affecting the sciatic nerve. Methods After patients' specific consent, we retrospectively reviewed the medical charts of all sciatic nerve endometriosis cases followed up at the Endometriosis Unit of La Paz University Hospital since 2006 to the present. We searched in our Unit of Endometriosis database and the inclusion criteria were: recurrent catamenial sciatica, in the absence of spinal pathology, MRI pointing to endometriosis as the cause of symptoms and