Pleomorphic adenoma is the most common parotid gland tumor and superficial parotidectomy with preservation of the facial nerve is the most common and appropriate treatment for most low-morbidity tumors.
PURPOSE:Evaluate and compare two different experimental techniques of maxillary sinus ostium occlusion using N-butyl cyanoacrylate in developing chronic histological findings without the inoculation of pathogenic bacteria among rabbits.
METHODS:In a randomized study, sixteen New Zealand rabbits were assigned for occlusion of the right maxillary sinus through a transmaxillary approach or through the roof of the nasal cavity. The contralateral sinus served as a control. After 12 weeks, the animals were sacrificed for blinded histopathological analysis of the maxillary sinus mucosa.
RESULTS:Histopathological changes consistent with CRS were found in eight (100%) of the maxillary sinuses approached transmaxillary and three of those through the roof of the nasal cavity (37.5%), p 0.008 and 0.250, respectively, comparing with the control side. Chronic mucosal changes were significantly better induced using the transmaxillary approach (p 0.026).
CONCLUSION:It is possible to induce a model of chronic sinusitis among rabbits with transmaxillary sinus occlusion without bacterial inoculation. This model can be replicated for future cellular studies.
A severe impairment of nutrition frequently occurs with morphological alterations in the oral cavity and the pharynx as well as with neurogenic disorders of the swallowing articulation. Complications like frequent aspirations are life-threatening. If the natural protection reflex for the respiratory tract, the cough reflex, does not work because of a reduced tracheal sensitivity, swallowing disorders often remain unrecognized. The ability of swallowing must be examined particularly with stroke-patients and weakened old patients. With radiological and endoscopic evaluations, oropharyngeal dysphagias can be assessed in detail. A wide spectrum of surgical measures and exercise treatment can clearly improve the life quality of the patients even if the aim, to make a complete and safe oral nutrition possible again, is not reached in every case.
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