Background: There is few medical literature regarding factors associated with remission after surgical and medical treatment of postoperative spine infections.Methods: Single-centre case-control study [2007][2008][2009][2010][2011][2012][2013][2014]. Cluster-controlled Cox regression model with emphasis on surgical and antibiotic-related parameters.Results: Overall, we found 66 episodes in 48 patients (49 episodes with metalwork) who had a median follow-up of 2.6 years (range, 0.5 to 6.8 years). The patients had a median of two surgical debridements.The median duration of antibiotic therapy was 8 weeks, of which 2 weeks parenteral. Clinical recurrence after treatment was noted in 13 episodes (20%), after a median interval of 2 months. In 53 cases (80%), the episodes were considered as in remission. By multivariate analyses, no variable was associated with remission. Conclusions:In patients with post-operative spine infections, remission is achieved in 80%. The number of surgical debridement or duration of antibiotic therapy shows no association with recurrence, suggesting that individual risk factors might be more important than the duration of antibiotic administration.

Objective: Describe the diagnostic work-up and postoperative results for patients treated by adrenalectomy for primary aldosteronism in France from 2010 to 2020 Summary Background Data: Primary aldosteronism (PA) is the underlying cause of hypertension in 6-18% patients. French and international guidelines recommend CT-scan and adrenal vein sampling as part of diagnostic work-up to distinguish unilateral PA amenable to surgical treatment, from bilateral PA that will require lifelong antialdosterone treatment. Adrenalectomy for unilateral primary aldosteronism has been associated with complete resolution of hypertension (no antihypertensive drugs and normal ambulatory pressure) in about 1/3 of patients, and complete biological success in 94% of patients. These results are mainly based on retrospective studies with short follow-up and aggregated patients from various international high volume centres. Methods: Here we report results from French-Speaking Association of Endocrine Surgery (AFCE) using the Eurocrine® Database. Results: Over 11 years, 385 patients from 10 medical centres were eligible for analysis, accounting for >40% of adrenalectomies performed in France for primary aldosteronism over the period. Preoperative work-up was consistent with guidelines for 40% patients. Complete clinical success (CCS) at last follow-up was achieved in 32% patients and complete biological success was not sufficiently assessed. For patients with two follow-up visits, clinical results were not persistent at one year for 1/5 patients. Factors associated with CCS on multivariate analysis were body mass index, duration of hypertension and number of antihypertensive drugs. Conclusions: These results call for an improvement in thorough preoperative work-up and long-term follow-up of patients (clinical and biological) to early manage hypertension and/or PA relapse.

Context: Staphylococcus aureus and coagulase-negative staphylococci (CoNS) are the most frequently isolated pathogens and are responsible for approximately two-thirds of joint replacement infections. Evidence Acquisition: Although both belong to the staphylococci genus, there are several epidemiological and therapeutic differences between S. aureus and the heterogenous group of CoNS. In general, however, preventive and therapeutic recommendations for Prosthetic Joint Infection PJI due to CoNS do not differ from PJI caused by other pathogens. Results: The main differences between the pathogens lie in the clinical presentation of PJI, the presumed origin of infection, and the presence of a higher proportion of methicillin-resistant strains leading to a limited choice of antibiotic agents. Conclusions: Fortunately, due to its lower virulence as compared to its cousin S. aureus, PJI due to CoNS may display higher remission rates than S. aureus-caused PJI after combined surgical and medical management.

Highlights Ectopic pancreatic tissue is a rare incidental finding during abdominal surgery. 80% of the lesions are unifocal and less than 3 cm in size. The most frequent site is the stomach, followed by duodenum and proximal jejunum. The imaging modalities and endoscopic biopsy often remain inconclusive. Only resection and and histopathologic examination provide the definitve diagnosis.