No abstract

Background. liver transplantation (ltx) is the ultimate treatment for some hepatologic patients (pts), very often observed having excessive weight gain after operation, resulting in an increased risk of non-communicable diseases (ncds). Objectives. the aim of the pilot study was to evaluate the chosen lifestyle risk factors of ncds (nutritional status, intake of energy, micronutrients, cholesterol and fiber, smoking habit and physical activity) of ltx pts. Material and methods. the pilot study group consisted of 44 pts (13 women and 31 men) of the department of transplant Medicine and nephrology, Medical university of warsaw. anthropometric, nutritional, smoking habit and physical activity data was collected from september 2015 till May 2016. Results. Mean body weight was 85.3 ± 15.6 kg, mean body mass index (BMi) -29.1 ± 4.5 kg/m 2 , mean waist circumference (wc) -101.9 ± 12.3 cm, mean % of total body fat -28.8 ± 7.9%. Only ca. 16% of pts had a normal BMi. More than 90% of pts had abdominal obesity. Mean energy intake was 1,605.4 ± 441.6 kcal (percentage of energy protein/total fat/carbohydrates -18.2 ± 3.2%/34.4 ± 5.8%/47.1 ± 6.0%), cholesterol intake 264.6 ± 100.7 mg, dietary fiber intake 17.4 ± 5.8 g daily. Mean number of steps was 7,163.2 ± 3,344.5 per day, and mean daily Met was only 1.5 ± 0.3. Moderate physical activity lasted on average for 02:06 ± 01:27 (hh:mm). the prevalence for smoking was 23%. Conclusions. the diet of ltx pts was based on improper proportions of macronutrients. anthropometric measurements of these patients revealed an impaired nutritional status, including metabolic obesity. the physical level of activity was insufficient. the prevalence for smoking was similar to the general Polish population. the presence of ncd risk factors among ltx pts requires the creation of interprofessional teams of health care workers. Key words: life style, liver transplantation, risk of non-communicable diseases.

The paper presents a study on functionalisation of multi-walled carbon nanotubes in the area of lattice defects and an attempt to bind the nanotubes with pitavastatin. Carbon nanotubes were synthesised by alcohol-chemical vapour deposition in the presence of the catalyst Fe-Co/MgO. The nanotubes were purified and the product was subjected to chemical functionalisation. Functional groups were introduced in the reaction of the purified nanotubes with thionyl chloride to obtain acidic chlorides linked to pitavastatin. The properties and structure of the nanotubes were analysed by FT-IR and Raman spectroscopies, transmission electron microscopy and liquid chromatography coupled with mass spectrometry. Photochemical stability of pitavastatin linked with carbon nanotubes has been found to be increased.