Purpose. To report a case of postoperative endophthalmitis caused by Fusarium species successfully treated with intravitreal and systemic voriconazole after treatment failure with amphotericin B. Methods. Clinical case report of a 60-year-old immunocompetent woman who presents with endophthalmitis of unknown origin 4 weeks after uneventful cataract extraction and IOL implantation surgery. IOL explantation, vitrectomy with capsular bag removal, vitreous aspiration for culture, and intravitreal injection of amphotericin B (5 μg/0.1 mL) were performed. Diagnosis was established by culturing the vitreous aspirate on a Sabouraud agar medium and staining with lactophenol blue solution. Five days later, there was no clinical response. The decision was made to administer a single dose of intravitreal voriconazole (2.5 μg/0.1 mL) and oral voriconazole (200 mg BID) for 30 days. Results. Fusarium sp. grew on culture. Treatment with local and systemic voriconazole was started after no improvement with vitrectomy, IOL explantation, and intravitreal amphotericin B. After 1 month of treatment, the infection resolved and best-corrected visual acuity was 20/25. Conclusion. In patients with endophthalmitis caused by Fusarium sp., topical and systemic voriconazole treatment should be considered in cases resistant to intravitreal amphotericin B.
To describe a novel, simple, and reproducible encircling scleral buckle technique based on Hamilton's controlled encircling procedure in order to standardize buckle height achievement in cases of retinal detachment. Methods: We describe a case series in which a novel modification of Hamilton's surgical technique was used, consisting of a typical encircling buckling procedure anchored in the center of each quadrant, with the ends of the band passed through a Watzke sleeve. Reference marks were placed to allow measurable shortening of the band when its ends were pulled to create an encircling indent. Postoperative ultrawide field retinal images were analyzed. Results: Our simple technique yielded predictable and reproducible postoperative scleral buckle heights. Shortening of the silicon band by 3, 4, 5, and 6.25 mm produced shallow indents, while additional shortening was considered excessive. Conclusion: Published studies about scleral buckle as a primary procedure or a combined technique with vitrectomy lack a uniform surgical technique. Our modification of Hamilton's technique uses objective measurements to generate a consistent and predictable postoperative buckle height.
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