Among patients with heart disease and LVEF < or =0.40, MTWA can identify not only a high-risk group, but also a low-risk group unlikely to benefit from ICD prophylaxis.

The degree of bone loss and the rates of fracture did not differ significantly between the intervention groups. Calcitriol was associated with a higher risk of hypercalciuria. Alendronate-treated patients sustained less bone loss at the spine than those in the reference group, and both intervention groups sustained less bone loss at the hip than the reference group. The requirement for monitoring the serum and urinary calcium levels in calcitriol-treated patients makes alendronate more attractive for the prevention of bone loss early after cardiac transplantation.

Strategies aimed at easing patients' adjustment to ICDs should be developed and tested for efficacy in the setting of ICD prophylaxis.

In patients with left ventricular dysfunction, an "indeterminate" MTWA test due to patient factors predicted death or SVA at least as well as a positive test.

Data from the National Longitudinal Survey of Youth reveal that approximately one-quarter of teenage mothers have a second child within 24 months of their first birth. The prevalence of closely spaced second births is greatest (31%) among young women whose first birth occurred prior to age 17. Teenage mothers' characteristics before the first birth (such as race or ethnicity and parents' level of education) and at the time of the first birth (such as years of schooling completed and whether their first birth was wanted) influence whether they have a rapid second birth. For example, those with more educated parents are less likely than others to have had a closely spaced second birth. In addition, young mothers who obtain additional schooling in the period after their first birth are less likely to have a closely spaced second birth, while those who marry are more likely to have a rapid second birth.