Many tools have been constructed using different formal methods to process various parts of a language specification (e.g., scanner generators, parser generators and compiler generators). The automatic generation of a complete compiler was the primary goal of such systems, but researchers recognized the possibility that many other language-based tools could be generated from formal language specifications. Such tools can be generated automatically whenever they can be described by a generic fixed part that traverses the appropriate data structures generated by a specific variable part, which can be systematically derivable from the language specifications. This paper identifies generic and specific parts for various language-based tools. Several language-based tools are presented in the paper, which are automatically generated using an attribute grammar-based compiler generator called LISA. The generated tools that are described in the paper include editors, inspectors, debuggers and visualizers/animators. Because of their complexity of construction, special emphasis is given to visualizers/animators, and the unique contribution of our approach toward generating such tools.
In this paper, we examine methods to classify hate speech in social media. We aim to establish lexical baselines for this task by applying classification methods using a dataset annotated for this purpose. As features, our system uses Natural Language Processing (NLP) techniques in order to expand the original dataset with emotional information and provide it for machine learning classification. We obtain results of 80.56% accuracy in hate speech identification, which represents an increase of almost 100% from the original analysis used as a reference.
Meningococcal meningitis remains a substantial cause of mortality and morbidity worldwide. Until recently, countries in the African meningitis belt were susceptible to devastating outbreaks, largely attributed to serogroup A Neisseria meningitidis (MenA). Vaccination with glycoconjugates of MenA capsular polysaccharide led to an almost complete elimination of MenA clinical cases. To understand the molecular basis of vaccine-induced protection, we generated a panel of oligosaccharide fragments of different lengths and tested them with polyclonal and monoclonal antibodies by inhibition enzyme-linked immunosorbent assay, surface plasmon resonance, and competitive human serum bactericidal assay, which is a surrogate for protection. The epitope was shown to optimize between three and six repeating units and to be O-acetylated. The molecular interactions between a protective monoclonal antibody and a MenA capsular polysaccharide fragment were further elucidated at the atomic level by saturation transfer difference NMR spectroscopy and X-ray crystallography. The epitope consists of a trisaccharide anchored to the antibody via the O- and N-acetyl moieties through either H-bonding or CH–π interactions. In silico docking showed that 3-O-acetylation of the upstream residue is essential for antibody binding, while O-acetate could be equally accommodated at three and four positions of the other two residues. These results shed light on the mechanism of action of current MenA vaccines and provide a foundation for the rational design of improved therapies.
The creation of Learning Spaces on the Web, like the exhibition rooms of virtual museums, supported by an ontology that enables a conceptual navigation over the learning objects exposed, is a hard and complex task but of uttermost importance for the success of the knowledge acquisition process. In our opinion, the creation must be systematic and reusable from case to case, based on the query of the ontology instances that describe the museum assets. We will discuss how the ontology definition drives the way SPARQL (SPARQL Protocol and RDF Query Language) queries extract information from the TripleStore to be prepared for visualization. However, to enable this approach, we need to populate the ontology in an automatic way, extracting the data from the annotated documents in the institution repository. We intend to show how that process can be implemented using the Museum of the Person (MP) as a case-study, describing the XML2RDF tool developed. To illustrate the complete approach proposed we will include a guided visit to the exhibition rooms of MP created according to that proposal and by our tools.
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