Hashimoto's encephalopathy is a rare disease which is thought to be autoimmune and steroid responsive. The syndrome is characterized by cognitive impairment, encephalopathy, psychiatric symptoms, and seizures associated with increased level of anti-thyroid antibodies. The exact pathophysiology underlying cerebral involvement is still lesser known. Although symptoms suggest a nonlesional encephalopathy in most of the cases, sometimes the clinical appearance can be subtle and may not respond to immunosuppressants or immunomodulatory agents. Here we report a case who presented with drowsiness and amnestic complaints associated with paroxysmal electroencephalography (EEG) abnormalities which could be treated only with an antiepileptic drug.
Objectives. The aim of the study was to examine the relation between clinical findings, neurological examination and electrophysiological studies in diagnosing carpal tunnel syndrome (CTS) and share our institutional experience in patients with CTS. Methods. Patients presenting with complaints of pain, paresthesia, and weakness in hands who diagnosed CTS between 2014 and 2015 were examined retrospectively. Demographic characteristics, clinical and neurological examination findings and electrodiagnostic evaluations were analyzed. Results. A total of 348 patients were included to the study. Weight and height measurements were significantly higher in patients with CTS on the right side (p=0.05 and p=0.04, respectively). Right hand side was the most dominant lateralization in patients with CTS (p=0.001) but there was no significant correlation for left side (p>0.05). The score of visual analogue scale was positively correlated with the severity of CTS (p=0.001). Thenar atrophy, hypoesthesia, positivity of Tinel and Phalen tests were also related to bilateral CTS (p=0.001 for each). Conclusion. We agree that clinical features, neurological examination findings and electrophysiological studies are effective diagnostic means in patients with CTS.
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