A novel and efficient visible-light-induced C(sp 2 )−H/N−H cross-dehydrogenative coupling (CDC)amination with both primary and secondary aliphatic amines at room temperature in air is developed. This photocatalytic reaction allows the direct formation of 3-aminoquinoxalin-2(1H)-ones via CDC-amination in the absence of any external oxidant added from outside. Preliminary mechanistic studies reveal that the present reaction proceeds through a radical process.

A convenient and practical metal-free visible-light-promoted method to synthesize 3-oxyalkylated quinoxalin-2­(1H)-ones was developed at room temperature. The present transformation could be accomplished through Rose Bengal-catalyzed C–H/C–H cross-dehydrogenative-coupling of quinoxalin-2­(H)-ones with simple ethers, providing an efficient and operationally simple method to access various 3-oxyalkylated quinoxalin-2­(1H)-ones with moderate to good yields.

A convenient visible-light-induced method for the synthesis of thiocarbamates from isocyanides, thiols, and water has been developed under mild reaction conditions. The present protocol offers a cost-effective and operationally straightforward approach to the various thiocarbamates in moderate to good yields by simple use of cheap Rose Bengal as the photocatalyst and water as the reaction reagent as well as an environmentally benign cosolvent.

Visible-light-mediated procedure has been developed for the synthesis of 3-acyl quinoxalin-2(1H)-ones through acridine red catalyzed decarboxylative acylation of α-oxo-carboxylic acids with quinoxalin-2(1H)-ones.

A novel visible-light-induced and Rose Bengal catalyzed strategy has been developed for the synthesis of α-ketoamides via decarboxylative acylations of isocyanides with α-oxocarboxylic acids and water under mild conditions.