Background: Because few studies have focused on the correlation between computed tomography (CT) signs and tumor grade in pseudomyxoma peritonei (PMP), we evaluated predictive value of abdominal enhanced CT in identifying high-vs. low-grade cases.Methods: In all, 75 patients diagnosed with PMP after surgery were consecutively recruited. The preoperative enhanced CT images were retrospectively analyzed for ascites, hepatic scalloping, omental and peritoneal lesion appearance, intralesional calcification and septa, and peripheral organ involvement. Logistic regression models were applied to analyze the relationship of CT signs with PMP grade. Receiver operating characteristic curves were generated to evaluate the potential utility of CT signs in detecting high-grade PMP.Results: Massive ascites (P=0.017) and peritoneal solid nodules (P<0.001) were more common in highgrade cases. Multivariate logistic regression identified massive ascites [odds ratio (OR) =4.389, 95% confidence interval (CI): 1.210-15.921; P=0.025] and peritoneal solid nodules (OR =19.932, 95% CI: 3.560-111.596; P<0.001) as independent predictors of high-grade PMP. For the 55 patients with hepatic scalloping, the maximum thickness of mucin deposition at the hepatic scalloping wave in high-grade PMP was thinner than that in low-grade PMP (P=0.021). Thickness of mucin deposition at the hepatic scalloping wave (OR =0.346, 95% CI: 0.148-0.809; P=0.014) was an independent predictor of high-grade PMP, with a cutoff value of 18.6 mm. Cancer antigen 125 (CA125) combined with CT signs was significantly better at diagnosing high-grade PMP than was CA125 alone in both the overall patients [area under the ROC curve (AUC): 0.812 vs. 0.656; P=0.020] and those with hepatic scalloping (AUC: 0.859 vs. 0.600; P=0.007). Conclusions:The CT signs of high-grade PMP significantly differ from those of low-grade PMP, and thus combining CT signs with CA125 may be highly valuable for classifying PMP.

ObjectiveAll spinal MR images obtained for patients ≥ 45 years, hospitalized from 1/6/2014--31/12/2015 were reviewed. VFs and fracture severity were classified using Genant's method. Data regarding VFs diagnosis, BMD by DXA, and initiation of osteoporosis treatment were extracted from each patient's MR reports and medical records. Methodsl Images were reviewed from 1040 patients (567 women, 55%). Mean age was 61.3 years. 265 patients (25%) were shown to have VFs. VFs was officially reported for only 89 patients (34%). 28 patients with reported VFs had bone marrow edema on MR, however edema was documented for only half of the patients (14/28). (Table 1) l Among 176 patients with unreported VFs, a total of 247 fractures were identified [mild: 224 (91%), moderate: 20 (8%), severe: 3(1%)]. (Table 2) l Of the 89 patients with VF, only 20 (23%) were subsequently referred for DXA, and only 49 (55%) had VFs mentioned among their discharge diagnoses. Only 28 cases (31%) were prescribed pharmacologic when discharged. (Table 1) l Of the 28 patients whose VFs were accompanied by bone marrow edema, only 6 had a subsequent DXA, and 14 were discharged on osteoporosis therapy. (Table 1