Adjuvant postoperative radiotherapy after anterior resection causes severe long-term anorectal dysfunction, which is mainly the result of a weakened, less sensitive anal sphincter and an undistensible rectum with reduced capacity.

This pilot study indicates that prucalopride can play an important role in the management of patients with CC due to SCI.

Background and Aims: major surgery is often followed by fatigue and reduced physical function. we wished to study if postoperativep hysical training reduced fatigue and improved physical function.Material and Methods: randomised, placebo-controlled, single-blinded study.P articipants were unselected patients ≥60y ears undergoing elective colorectal surgery without disseminated cancer or inflammatory bowel disease. Group Atrained muscular strength and work capacity.g roup bp erformed relaxation exercises and received hot wrappings and massage. main outcome measures were: fatigue (visual analogue scale), muscular strength, walking speed, physical performance test, and physical function questions (SF-36).Results: Preoperatively the two groups were similarexcept that awas more fatigued than b. by postoperative day seven fatigue had increased compared to preoperatively, more in Bt han A, but by day 30 and 90 there were no significant differences between groups.all indices of physical function decreased postoperative day seven and were at the preoperative level day 90 with no significant differences between groups in change in function. day seven the change in knee extension strength tended to be lower in b than Abut by day 30 changes were similarinboth groups.Conclusion: Postoperative training did not improve physicalf unction, but reduced fatigue in hospital.

Survival and mortality from colon and rectal cancer improved before the National Cancer Plan was proposed; after its implementation, however, improvement has been observed for rectal cancer only.