Zika virus (ZIKV) infection has been associated with Guillain-Barré Syndrome (GBS). Roughly 60% of people in countries such as the U.S. live in areas at risk for seasonal spread of ZIKV. ZIKV belongs to a class of diseases that is not typically seen in hospital settings across the U.S. and Europe. We describe the case presentation, management, and treatment of ZIKV infection complicated by GBS. A 64-year-old woman with recent travel to the Dominican Republic presented with rash followed by an acute, ascending polyneuropathy consistent with GBS. She was confirmed to have an acute ZIKV infection by detection of ZIKV nucleic acid by reverse transcription-polymerase chain reaction. She met Brighton Collaboration criteria level 1 evidence for GBS. She received two courses of intravenous immunoglobulin and slowly improved, though still had weakness at discharge. More research is needed to identify the pathophysiology behind ZIKV-associated GBS and its optimal treatment. Prevention is fundamental to limiting infection and spread of ZIKV.
a normal examination in the same patient. References 1. 2.3. 4. 5. 6. 7.8. 9. 10. 11. 12. 13.14. 15. 16. 17.18. Sandyk R. The endogenous opioid system in the neurological disorders of the basal ganglia. Life Sci 1985;37:1655-1663. Bosse A, Kuschinsky K. Alterations of dopaminergic neurotransmission after chronic morphic treatment: pre-and postjunctional studies in striatal tissue. Arch Pharmacol Das D, Rogers J, Michael-Titus AT. Comparative study of the effects of mu, delta and kappa opioid agonists on 3Hdopamine uptake in rat striatum and nucleus accumbens. Neuropharmacology 1994;33:221-226. Funada M, Suzuki T, Misawa M. The role of dopamine DIreceptors in morphine-induced hyperlocomotion in mice. Neurosci Lett 1194;169:1-4. Nutt JG, Rosin AJ, Eisler T, Calne DB, Chase TN. Effect of an opiate antagonist on movement disorders. Arch Neurol 1978;35:810-811. Wasserman S , Yarhr MD. Choreic movements induced by the use of methadone. Arch Neurol 1980;37:727-728, Lieberman AN, Goldstein M. Reversible parkinsonism related to meperidine. N Engl J Med 1985;312:509. Christian CM, Waller JL, Moldenhauer CC. Postoperative rigidity following fentanyl anesthesia. Anesthesiology 1983; Scott JC, Sarnquist FH. Seizure-like movements during a fentanyl infusion with absence of seizure activity in a simultaneous EEG recording. Anesthesiology 1985;62:812-814. Mirenda J, Tabatabai M, Wong K. Delayed and prolonged Ref e r e n c e s
In medical education, professionalism and interpersonal communication skills are considered to be equally important to the mastery of medical fund of knowledge. 1,2 The American Association of Medical Colleges states that "medical schools should articulate and defend the importance of professional values," and suggests tools for developing and assessing these skills, such as 360-degree evaluations, simulations, clinical vignettes, retreats, and focus groups. 1 The Accreditation Council for Graduate Medical Education includes interpersonal communication and professionalism as core competencies; trainees must achieve these before practicing independently. 2 This emphasis on professionalism and communication competencies may be related to data showing a link between excellence in communication skills and improved medical outcomes. Such outcomes include increased patient satisfaction and trust, increased patient adherence with treatments, increased likelihood patients will stay with a physician, fewer patient complaints, and reductions in the frequency of litigation. 3 Furthermore, unprofessional behavior is associated with reduced productivity among colleagues, high physician turnover, and propensity for physician burnout. 4 Despite their importance, the best methods for teaching professionalism and communication skills remain unclear. We sought to (1) assess the self-reported comfort level of neurology residents with professionalism and communication tasks; (2) identify how neurology residents feel that they learn best; (3) explore faculty's perception of teaching residents about professionalism and communication; and (4) pilot a novel educational initiative to improve professionalism and communication skills for our residents. Methods Anonymous electronic surveys were distributed to neurology residents and faculty in the Department of Neurology at our institution in October 2017. Surveys were designed to assess perceptions regarding resident education on interpersonal communication and professionalism tasks, including specific scenarios such as breaking bad news, delivering a sensitive diagnosis, discussing prognosis, leading a goals-of-care discussion, disclosing a medical error, reviewing risks and benefits of IV tissue plasminogen activator (tPA), and communicating with members of the care team (see supplemental data, links.lww.com/WNL/B39). After review of the survey results, a committee of faculty members and residents discussed how to improve resident education about communication and professionalism. Due to the study's design, review by the institutional review board was waived. Based on survey results (discussed in the following section), we designed a program of performance-based assessment to augment our existing didactic on professionalism and
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.