Penile intraepithelial neoplasia (PIN) is a clinically well known condition. However, its diagnosis is often diYcult. We present four cases of PIN, seen in our department. Various histological patterns ranging from PIN I to PIN III were noted in these cases. (Sex Transm Inf 1999;75:435-436)

Concomitant infection of Neisseria gonorrhoeae and Chlamydia trachomatis is frequent and it is common practice to prescribe ancillary treatment for chlamydial infection when infection with N. gonorrhoeae is suspected or confirmed. In Coventry cases are treated as they are diagnosed. Our objective was to determine the clinical effectiveness of treating gonorrhoea and chlamydial infection separately in cases of co-infection. Case notes of co-infection with N. gonorrhoeae and C. trachomatis diagnosed in Coventry GU clinic from March 1989 to February 2000 were reviewed retrospectively. There were 1250 episodes of gonorrhoea, 4127 of chlamydial infections, and both infections were found in 332 cases. The two infections were treated in 322 cases and in 235 cases were treated separately. Ten cases did not come back for treatment of chlamydial infection, which is less than one case per year and 0.2% of total chlamydial infection in 11 years. On the other hand, 918 (73%) of total number of gonorrhoea patients did not have to take unnecessary treatment for chlamydial infection. In some clinical settings co-infection with N. gonorrhoeae and C. trachomatis could be treated separately with significant success and in the long run this might prevent development of antibiotic resistance of C. trachomatis infection.

SUMMARYA 21-year-old, usually fit and well man, presented with a 10-year history of intermittent, paroxysmal pain and temperature sensitivity to his right thumb. He felt this was associated with a subungual lesion present on the same digit. He was diagnosed as having a glomus tumour and was referred to the hand surgeons for surgical excision. BACKGROUND

No abstract