Venous occlusion plethysmography was used to measure the effect of changes in limb position on the peripheral blood flow. The validity of the method with the limb dependent was investigated, and found to be reliable in the conditions of the experiment. The blood flow in the limb was found to be decreased when it was raised or lowered 45 degrees. At 15 degrees of elevation, the flow was increased. Similar changes were found in recently sympathectomized limbs. The reactions may therefore be regarded as local vascular responses to postural change.
Plasma levels of insulin and human growth hormone (HGH) were measured in healthy adults after oral or intravenous administration of the pentose sugar D-ribose. Increased plasma levels of insulin were recorded after both oral and intravenous ribose; there was no consistent change in plasma levels of HGH after administration of ribose by either route. It is suggested that insulin release occurs at such times and in amounts as may account at least in part for the hypoglycemie effect of this pentose.
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