The aim of this meta-analysis, based on individual participant data from several studies, was to investigate the influence of patient-, materials-, and tooth-related variables on the survival of posterior resin composite restorations. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we conducted a search resulting in 12 longitudinal studies of direct posterior resin composite restorations with at least 5 years' follow-up. Original datasets were still available, including placement/failure/censoring of restorations, restored surfaces, materials used, reasons for clinical failure, and caries-risk status. A database including all restorations was constructed, and a multivariate Cox regression method was used to analyze variables of interest [patient (age; gender; caries-risk status), jaw (upper; lower), number of restored surfaces, resin composite and adhesive materials, and use of glass-ionomer cement as base/liner (present or absent)]. The hazard ratios with respective 95% confidence intervals were determined, and annual failure rates were calculated for subgroups. Of all restorations, 2,816 (2,585 Class II and 231 Class I) were included in the analysis, of which 569 failed during the observation period. Main reasons for failure were caries and fracture. The regression analyses showed a significantly higher risk of failure for restorations in high-caries-risk individuals and those with a higher number of restored surfaces.

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The summarized scanning electron microscopic-supported micromorphologic data of a 10-year longitudinal clinical study of GIC/Hybrid composite posterior restorations is reported. The aim of this study was to compare the results to USPHS-compatible clinical criteria of the CPM index and to analyse the deterioration pattern and the success rate. Out of a total of 194 Class I and Class II fillings 46 restorations were at baseline, after 1, 3, 5, 7 and 10 years. The restorations were micromorphologically examined using gold-sputtered replicas and coded according to the M-criteria of the CPM index. The features for surface roughness, surface texture, marginal integrity, excess of material, marginal fracture, loss of material, marginal leakage and other filling imperfections were assessed. Eighteen fillings showed perfect margins, rapidly deteriorating after the first year of service. Despite poor micromorphologic marginal conditions all restorations retained optimal functional characteristics. Parallel longitudinal micromorphologic and clinical assessment of posterior GIC/Composite restorations revealed fine structure and deterioration patterns of the tooth-biomaterial interface. The layer-technique using GIC as dentine replacement and resin-based composite as enamel replacement results, according to previous biocompatibility testing, and clinical data, in optimal pulp protection and correct anatomic form over a 10-year period. The myth of the need for perfect marginal integrity requires further discussion.

The periodontal condition of 123 poodles was assessed using the parameters of depth of gum pocket, attachment level, bleeding on probing, and plaque and calculus accumulation. No dogs were free of periodontal disease. The number of deep pockets and dramatic loss of attachment ranged from 0.1 teeth in young dogs to 4.2 teeth in old animals. A sixfold increase in deep pocketing took place in dogs between the ages of six and seven, followed by a twofold increase in the number of teeth missing in dogs within the 10 to 11 year age group. First premolars, incisors and second molars were at highest risk. No correlation between dietary conditions and disease incidence could be detected. It is concluded that, by concentrating their diagnostic efforts on those age groups and types of teeth at highest risk, clinicians could improve the effectiveness of their treatment interventions.

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