Twenty-eight fungal feruloyl esterases (FAEs) were evaluated for their synthetic abilities in a ternary system of n-hexane: t-butanol: 100 mM MOPS-NaOH pH 6.0 forming detergentless microemulsions. Five main derivatives were synthesized, namely prenyl ferulate, prenyl caffeate, butyl ferulate, glyceryl ferulate, and L-arabinose ferulate, offering, in general, higher yields when more hydrophilic alcohol substitutions were used. Acetyl xylan esterase-related FAEs belonging to phylogenetic subfamilies (SF) 5 and 6 showed increased synthetic yields among tested enzymes. In particular, it was shown that FAEs belonging to SF6 generally transesterified aliphatic alcohols more efficiently while SF5 members preferred bulkier L-arabinose. Predicted surface properties and structural characteristics were correlated with the synthetic potential of selected tannase-related, acetyl-xylan-related, and lipase-related FAEs (SF1-2, -6, -7 members) based on homology modeling and small molecular docking simulations.

No abstract

No abstract

A New Stereoselective Route to Branched-Chain Nitro and Amino Sugars: Synthesis of Both Enantiomers of Decilonitrose and Avidinosamine.-Readily accessible oximino ethers such as (III) or (IX) serve as key intermediates in the diastereoselective synthesis of branched-chain amino and nitro sugars such as the methyl glycosides (VI) and (XII) of (D)-and (L)-decilonitrose or the glycoside (XI) of (L)-avidinosamine. -(GREVEN, R.; JUETTEN, P.; SCHARF, H.-D.; J.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.