Patients in various clinical states of diabetes mellitus (according to the recommendation of the American Diabetes Association) as a primary diagnosis were examined for fungal infections by Candida species. Candida spp. were detected in urine, in the material taken from the mouth cavity, nails, skin lesions, ears and eyes, by cultivation on the Sabouraud agar, CHROMagar Candida, and by saccharide assimilation. In the group of diabetics with symptoms of oral candidiasis and denture stomatitis C. albicans was identified in 8 cases, C. tropicalis in 3, C. parapsilosis in 2; 1 strain of C. guilliermondii was also isolated. In patients with urinary tract infections the presence of C. albicans was shown in 12 cases; C. parapsilosis was detected in 6 cases and two strains of each C. tropicalis and C. krusei were also isolated. In patients with leg ulcers C. albicans (25 cases), C. parapsilosis (5), C. tropicalis (3) and one strain of each C. krusei and C. robusta were isolated. Otomycosis was associated with one strain of C. albicans, C. parapsilosis, C. tropicalis and C. guilliermondii. C. albicans was most frequently associated with onychomycosis, paronychia and endophthalmitis; C. parapsilosis was the second most rated yeast.

Pandemic management increases the burden on healthcare workers to provide care and also affects their personal lives, with dentists being at particular risk. Therefore, we aim to describe the quality of life (QoL) and limitations experienced due to pandemic management-related measures (PanMan), as well as to assess the association of PanMan with QoL during the first lockdown after the coronavirus outbreak. We obtained data from 500 dentists (33.2% males, M/SD = 43.8) registered with the Slovak Chamber of Dentists using an online questionnaire. We categorized PanMan as the availability of personal protective equipment (PPE) and the ability to implement anti-pandemic measures, information overload, pandemic-related limitations and QoL in terms of their impact on family life and activities, housekeeping, relationships with relatives, financial situation and mental well-being. PanMan mainly affected financial situation, mental well-being and housekeeping. Factors contributing most towards the worsening of QoL were information overload (odds ratio/95% confidence interval, OR/CI: 5.79/2.64–12.71) and several pandemic-related limitations. These consisted of (OR/CI): a lack of PPE (5.17/2.48–10.77), infection risks in the work environment (3.06/1.57–5.95), obligatory safety measures (3.02/1.47–6.21), lack of staff (2.85/1.30–6.25) and client concerns (3.56/1.70–7.49). Pandemic management has led to a considerable worsening of dentists’ QoL.

Tick-borne encephalitis (TBE) is caused by tick-borne encephalitis virus (TBEV), a virus species of the genus Flavivirus within the Flaviviridae family. In Western Europe, TBEV is transmitted primarily by the Ixodes ricinus (I. ricinus) tick. During the last 30 years, there has been a continued increase in human cases of TBE in Europe. A total number of 102 cases in Slovakia was reported in 2012 (1.89/100,000), with two local outbreaks after the ingestion of raw milk and dairy products. Active vaccination is the most effective method of preventing TBE. According to the available data in Slovakia from 2012, 8,491 children under 15 years of age were vaccinated that year, which, when compared to 2009 with approximately 17,000 vaccinated children, represents a decrease of more than 50%. The data on vaccination of adults are not available, but the estimated vaccination coverage in Slovakia is around 1% (1.3/100,000). The education of the population is also an important precautionary measure in the prevention of tick-borne illnesses.

Information on mechanical properties of human enamel and dentin and effect of load on their deformation and damage tolerance is very important in the development of successful dental materials. In this study, the hardness, indentation modulus and deformation characteristics of tooth have been investigated across the lingual–buccal enamel and dentin cross‐section by instrumented indentation up to 1500‐nm indentation depth. We realized and examined the distribution of hardness and modulus at different areas of enamel and dentin with the aim to understand deformation behaviour at these different locations. Scanning electron microscopy was used for the microstructure characterization of the enamel and dentin and their deformation behaviour. Raman spectroscopy analyses were carried out for determination of the enamel and dentin composition as well. The average values of hardness and modulus for enamel in the occlusal area are 5.35 ± 0.19 and 98.1 ± 1.5 GPa, in the inner area 3.68 ± 0.5 and 81.8 ± 5 GPa and in the area close to the dentin–enamel junction 2.83 ± 0.27 and 71.4 ± 4.1 GPa, respectively. The average values of hardness and modulus of dentin in the area close to the dentin–enamel junction are 0.71 ± 0.05 and 21.27 ± 0.76 GPa and in the inner area 0.65 ± 0.06 and 19.79 ± 0.93 GPa, respectively. The effect of the indentation location on deformation and mechanical properties was clarified.

Background The COVID-19 pandemic led to accepting a lot of various protective pandemic management-related measures (PanMan), which may have had a large impact on health care workers (HCWs) but evidence is scarce. We therefore explored the impact of measures during the second wave. We assessed the associations of PanMan with the Quality of Life (QoL) of hospital HCWs. Methods We collected data from 215 HCWs (77.7% females, mean age 44.4), who were working at the COVID-related departments of one large hospital in eastern Slovakia via a questionnaire, specifically developed in direct collaboration with them. We assessed PanMan related factors, such as COVID-19 experience, information overload, non-adherence of the public, work stress, barriers and facilitators of health care provision, and QoL related factors, such as impact on family life and activities, housekeeping, relationships with relatives and mental well-being. To analyse the data, we used logistic regression models adjusted for age and gender. Results PanMan greatly impacted the QoL of HCWs, in particular family life, housekeeping and mental well-being (odds ratio, 6.8–2.2). The most influential PanMan factors were COVID-19 experience (3.6–2.3), work stress (4.1–2.4) and barriers in health care provision (6.8–2.2). Perceiving work stress had a negative impact on all QoL domains, even on relationships with the greatest impact. Conversely, the PanMan factors reducing the negative impact on QoL were training and colleagues’ support (0.4–0.1). Conclusion PanMan had a strong negative impact on the QoL of hospital HCWs during the second wave of the COVID-19 pandemic.