There are a variety of conditions that manifest not only in bone but also in skin. Bone and skin structures can share common embryologic origins, and genetic defects that occur early in cell differentiation may lead to disease in both organ systems. Alternatively, diseases of bone and skin may be caused by defects in genes that participate in directing or controlling both systems. Many diseases of bone and skin can manifest with atypical radiologic findings or mimic malignant bone lesions. Upon encountering such a disease process, a radiologist who is familiar with both aspects of the disorder and consequently looks for associated skin findings can greatly benefit the patient by making a definitive diagnosis. Similarly, a clinician who encounters suggestive skin lesions should be prompted to look for concomitant skeletal lesions. By synthesizing knowledge of bone and skin manifestations, radiologists and clinicians can help correctly diagnose a number of these disease processes, thereby helping patients avoid further, often nonspecific invasive workup and advancing patient care.

Askin tumor is a rare disease which had previously been reported as being thallium-201 and gallium-67 avid. Varying data regarding 18F- fluorodeoxyglucose metabolism has been described with Ewing family of soft tissue tumors. In this case, we present a patient found to have an Askin tumor of the left chest wall which demonstrated indium-111 pentetreotide and technetium-99m MIBI avidity. The lesion did not show 18F- fluorodeoxyglucose hypermetabolism in this case despite the aggressiveness of the tumor. The patient was treated with surgical excision of the tumor and chemotherapy. Subsequently, contrast enhanced CT, indium-111 pentetreotide and technetium 99m-MIBI showed that the lesion had regressed. These findings suggest that Askin tumor can demonstrate Indium-111 pentetreotide and technetium 99m-MIBI uptake and need not be hypermetabolic on 18F-fluorodeoxyglucose exam.

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Outlines the position of the gun in American society. Considers the benefits and issues this brings covering the present actions of the National Rifle Association and the Handgun control lobbies. Briefly looks at recent change in the law in different states. Provides some thoughts on the implications for business, suggesting measures which can be introduced and policies for employees.

Violence and crime are major issues facing America today. Every night news programmes highlight stories of rape, homicides, gangs, drug use, and other criminal activities. It seems that crimes are becoming more violent. Activities like burglary and purse snatching are no longer newsworthy events. In addition, car jackings and home invasions seem like normal occurrences unless there is a killing involved. Guns are also playing a bigger role in criminal activities. In most metropolitan areas, gang shootings seem like normal events. In high school and junior high, students are found with weapons. Fellow students are afraid to report them for fear of reprisal. Unless your life is immediately threatened, police departments will not respond immediately to your call. It often takes 24 hours for the police to respond to a report of a car theft or home burglary. Law enforcement agencies do not have the resources to respond as quickly as before. Budgetary cutbacks and outdated equipment are limitations that local law departments are facing in today's economy. In addition, law enforcement's task is tougher today than previous decades. Human rights groups monitor police activities and records for violations. Every night we hear of defence lawyers getting their clients off on technicalities. The people in the United States are becoming frustrated with all the criminal behaviour. What can be done? Why do not people respect each other? Solutions range from social programmes to tougher sentences. In today's environment there are many groups that feel that they should have the right to defend themselves. The ability to carry a concealed weapon is a controversial issue facing society. Individuals feel that the constitution guarantees them the right for self-protection. Opponents feel that armed citizens will only endanger the public. The ability to legally carry a firearm is becoming more prevalent in the United States and businesses must become aware of the implications.