Alzheimer's disease (AD) is one of the most common forms of dementia, which cannot be cured at the moment. Therefore, researchers also look for the alternative approaches to its treatment. It is suggested that changes in human gut microbiome mediated by exercise could influence the development and progression of AD and a new term "muscle-gut-brain axis" is introduced. There is much evidence to support this assumption. The gut microbiology is closely related to a wide range of diseases of the nervous system and therefore any negative qualitative and quantitative changes in the composition of the gut microbiota can potentially contribute to the pathophysiology of AD. Research shows that the treatment of intestinal dysbiosis with probiotics/synbiotics/eubiotics can prevent or alleviate the symptoms of these chronic neurological diseases. Studies also point to the positive effects of movement on the health of seniors. A positive correlation can be found between cognitive functions and physical stress, both in the elderly and in AD patients. Even short-term interventions with a relatively low frequency seem to produce positive results, while physical activities can be performed by using relatively simple and cost-effective means. In addition, physical activity can significantly modulate gut microbiome. Thus, it can be concluded that physical activity in humans seems to correlate with gut microbiome, which can prevent the incidence and development of AD.

CrossFit is one of the fastest growing sports. Its growing popularity also applies to its competition form. This pilot study aims to analyse strength, endurance performance and their relationship to the resulting ranking in the CrossFit Open. Furthermore, the forms of training of elite Czech crossfitters are described in more detail. The research sample consisted of the 20 best Czechs (average height, age, and bodyweight of 180cm, 28.5 years and 90.7 kg respectively) according to the CrossFit Open ranking. The questionnaire was used to collect information regarding the training regime and their current performance parameters. Descriptive statistics include the correlation between individual performances and overall ranking. Crossfitters had very good strength parameters in exercises with external load and also with their bodyweight (average values: clean and jerk 141.5 kg, snatch 113.9 kg, back squat 184.1 kg, strict press 87.2 kg, deadlift 217.9 kg, strict handstand push-ups 21.5 reps., pull-ups 20.6 reps.). The Olympic weightlifting performance (snatch and clean and jerk) was the strongest predictor for placing (-.606 resp.-.625, α=.01). The weekly training time was 800-900 minutes and contained mostly combined training units with a total of 9.2. Given the interesting results achieved in this pilot study, more detailed and validated studies are needed.

At present, due to the demographic changes and the rise of senior population worldwide, there is effort to prolong an active life of these people by both pharmacological and non-pharmacological strategies. The purpose of this article is, on the basis of the literature review of recent clinical studies, to discuss one of such strategy, i.e., the effect of Mediterranean Diet (MedDiet) on the cognitive functions among both the cognitively unimpaired and impaired elderly people. The methodology includes a literature review of full-text, peer-reviewed journal studies written in English and published in Web of Science and PubMed between 1 January 2016 and 28 February 2021. The findings indicate that the adherence to MedDiet has a positive effect on both cognitively impaired and unimpaired older population, especially on their memory, both in the short and long run. The results show that the higher adherence to MedDiet proves to have a better effect on global cognitive performance of older people. In addition, the adherence to MedDiet offers other benefits to older people, such as reduction of depressive symptoms, lowered frailty, as well as reduced length of hospital stays.

No abstract

SummaryCrossFit is one of the sports disciplines where endurance play a significant role in the performance. For testing anaerobic fitness it is important to choose the means that are part of the exercise and have a good transfer to the sport. A sample of competitive crossfitters (n = 12) underwent stress tests on the assault air bike (AB) (60 s) and Wingate. In addition to the performance parameters (Wmax, Wmean, W/kg, cal), lactate values after exercise (1st, 5th, 10th and 15th minute) were monitored. The results showed significant differences in both the absolute values of lactate and the development of the lactate curve (α = 0.05). The correlation of the selected variables showed a significant relationship between the average Watts value and the calories traveled (0.894). Testing anaerobic fitness with AB appears to be a suitable variant for CrossFit, as well as monitoring the development of lactate curve. Due to the original design of the study, it is necessary to verify the results.