This study was conducted to summarize the results of studies investigating the role of neutrophil to lymphocyte ratio (NLR) in epilepsy. The search was conducted on PubMed, Scopus, and Web of Science up to December 25, 2021. Finally, a total of seven studies were included in the review. The NLR in patients who were in the acute phase was higher than that of healthy. NLR in the patients who were in either acute or subacute phase was higher than in healthy controls. A significant difference in NLR levels between the acute and subacute phases was also noted. Epilepsy is one of the most important neurological diseases in the world, and millions of people around the world suffer from it, and a cheap and fast biomarker is needed for it. The interesting thing is that inflammation plays a role in epilepsy, and elevated NLR value can be a good biomarker of inflammation and, as a result, for epilepsy.

Background and aim: the aim of present study was Assessing the Overall Postoperative morbidity among patients with brain tumors by using preoperative functional Magnetic Resonance Imaging. Method: Databases of PubMed, Scopus, Web of Science, EBSCO, ISI Web of knowledge and Embase were searched for systematic literature between 2012 to July 2022.  95% confidence interval for odds ratio with fixed effect model and Mantel–Haenszel method and were calculated. To deal with potential heterogeneity, random effects were used and I2 showed heterogeneity. Meta-analysis was performed using Stata/MP v.17 software. Result: In the initial review, duplicate studies were eliminated and abstracts of 178 studies were reviewed, the full text of 32 studies was reviewed by two authors, finally, six studies were selected. Odds ratio of Unfavorable outcomes between functional MRI and control group was 0.46 (OR, 95% CI 0.15, 0.76; p<0.001). Odds ratio of Gross total resection between functional MRI and control group was 0.20 (OR, 95% CI -0.20, 0.59; p=0.34). Conclusion: According to the findings of the present study, the use of functional MRI before brain tumor removal is associated with a reduction in the risk of delayed or permanent neurological deficits after surgery with a two-month follow-up period.