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The communities within Binh Dinh province in the Central Vietnam are reliant on groundwater as their primary supply of domestic and potable water. Meanwhile, it is seriously contaminated with fluoride that causing fluorosis problem for people. This study aims to investigate the link between severity of dental fluorosis rate in a population and fluoride concentration in drinking water in Tay Son area. A total of 50 well-water samples were collected and 220 people were surveyed by questionnaire from 50 households at 3 villages: Tay Phu, Binh Tuong, Tay Giang of Tay Son district, Binh Dinh province, Vietnam. The quantitative assessment of severity of dental fluorosis was done by calculating the Community Fluorosis Index (CFI) using Dean's classification. Result of this study showed that fluoride concentration in well-water varied from 0.31 mg/L to 7.69 mg/L (mean 2.66 mg/L, SD: 2.18 mg/L) with 70 % of well-water samples above the maximum permissible limit of 1.5 mg/L of World Health Organization (WHO) drinking water standard. 100 % people surveyed was suffered from dental fluorosis and Dean scale of dental fluorosis ranged from level 2 to level 5. CFI varied from 3.45 to 4.13 above limit value (0.6). The community seriously suffered from dental fluorosis. The fluoride concentrations and Dean Index have high correlation (r = 0.580, p < 0.0001). Based upon results of this study, it is recommended that the government should supply drinking water with appropriate fluoride content for this community.