The study aims to investigate the effects of the spatial configuration of traditional Vietnamese houses on the design of apartment buildings in Ho Chi Minh (HCM) City, Vietnam. To achieve the objective, the following approaches were implemented. Firstly, the transformation of the socio-economic structure in HCM City, which is a primary factor affecting the development of apartment buildings was examined. Secondly, the well-known space syntax method for analyzing the spatial structure plan was outlined. Thirdly, a survey of traditional houses and apartment buildings from 1960 to 2010 was conducted. Among the various traditional house styles, the Hue traditional garden house, which has primary effects on the modern housing design in HCM City, was selected as a representative sample to compare with apartment units. Lastly, the space syntax method was employed to analyze the spatial structure of the sample of traditional houses and apartment units. The effects of the Hue traditional house?s spatial configuration on apartment buildings were analyzed. The result shows that the spatial configuration of modern apartment buildings and traditional houses have similar characteristics, including having an adaptable natural environment, and they both reflect Vietnamese culture and society. The findings can be applied when predicting development trends for the unit plans of modern apartments in HCM City, Vietnam.

Aim: This study was designed to investigate the anti-nociceptive effect of Morus alba stem extract as well as its cartilage protective effect in the anterior cruciate ligament transection (ACLT)-induced rat model of osteoarthritis (OA). Methods: The anti-nociceptive effect of this plant extract was determined by measuring hind limb weight bearing, while the severity of cartilage damage to the knee joints was evaluated using the modified Mankin grading system. Results: Oral administration of M. alba stem extract (56 and 560 mg/kg) significantly attenuated joint pain as indicated by a significant (p < 0.05) increase in the values of percent weight borne on the operated hind limb for the OA-induced groups that received M. alba stem extract at 56 and 560 mg/kg when compared to those of the vehicle-treated OA-induced group. In addition, a significant improvement in the Mankin score was also observed in rats treated with 560 mg/kg M. alba stem extract, which was in agreement with its pain-relieving effect. Conclusion: The results showed that M. alba stem extract exhibited an anti-nociceptive effect as well as cartilage protection in the ACLT-induced rat model of OA, supporting its potential use as a therapeutic treatment for OA.

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