Transfer learning schemes based on deep networks which have been trained on huge image corpora offer state-of-the-art technologies in computer vision. Here, supervised and semi-supervised approaches constitute efficient technologies which work well with comparably small data sets. Yet, such applications are currently restricted to application domains where suitable deep network models are readily available. In this contribution, we address an important application area in the domain of biotechnology, the automatic analysis of CHO-K1 suspension growth in microfluidic single-cell cultivation, where data characteristics are very dissimilar to existing domains and trained deep networks cannot easily be adapted by classical transfer learning. We propose a novel transfer learning scheme which expands a recently introduced Twin-VAE architecture, which is trained on realistic and synthetic data, and we modify its specialized training procedure to the transfer learning domain. In the specific domain, often only few to no labels exist and annotations are costly. We investigate a novel transfer learning strategy, which incorporates a simultaneous retraining on natural and synthetic data using an invariant shared representation as well as suitable target variables, while it learns to handle unseen data from a different microscopy technology. We show the superiority of the variation of our Twin-VAE architecture over the state-of-the-art transfer learning methodology in image processing as well as classical image processing technologies, which persists, even with strongly shortened training times and leads to satisfactory results in this domain. The source code is available at https://github.com/dstallmann/transfer_learning_twinvae, works cross-platform, is open-source and free (MIT licensed) software. We make the data sets available at https://pub.uni-bielefeld.de/record/2960030.

Over the last years, word and sentence embeddings have established as text preprocessing for all kinds of NLP tasks and improved the performances significantly. Unfortunately, it has also been shown that these embeddings inherit various kinds of biases from the training data and thereby pass on biases present in society to NLP solutions. Many papers attempted to quantify bias in word or sentence embeddings to evaluate debiasing methods or compare different embedding models, usually with cosine-based metrics. However, lately some works have raised doubts about these metrics showing that even though such metrics report low biases, other tests still show biases. In fact, there is a great variety of bias metrics or tests proposed in the literature without any consensus on the optimal solutions. Yet we lack works that evaluate bias metrics on a theoretical level or elaborate the advantages and disadvantages of different bias metrics. In this work, we will explore different cosine based bias metrics. We formalize a bias definition based on the ideas from previous works and derive conditions for bias metrics. Furthermore, we thoroughly investigate the existing cosine-based metrics and their limitations to show why these metrics can fail to report biases in some cases. Finally, we propose a new metric, SAME, to address the shortcomings of existing metrics and mathematically prove that SAME behaves appropriately.

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Pre training of language models on large text corpora is common practice in Natural Language Processing. Following, fine tuning of these models is performed to achieve the best results on a variety of tasks. In this paper we question the common practice of only adding a single output layer as a classification head on top of the network. We perform an AutoML search to find architectures that outperform the current single layer at only a small compute cost. We validate our classification architecture on a variety of NLP benchmarks from the GLUE dataset. The source code is open-source and free (MIT licensed) software, available at https://github.com/TheMody/NASforSentenceEmbeddingHeads.* We gratefully acknowledge funding by the BMWi (01MK20007E), from the MKW NRW in the project Bias aus KI-Modellen and by the BMBF (01IS19080 A).

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