Introduction: Cervical cancer is the most common cancer among women living with HIV with the highest burden in sub-Sahara African countries with the highest prevalence of HIV. Early detection of precursor cervical lesions through routine Pap smear screening is central to cervical cancer prevention. This study was aimed at determining the prevalence and predictors of abnormal Pap smear findings among women with HIV in our cervical cancer screening program. Methodology: We carried out a cross sectional study of adult women with HIV who presented for Pap smear test for the first time at the Jos University Teaching Hospital, Jos, North Central Nigeria between November2018 and January 2020. Prevalence of abnormal cervical finding was reported in percentage and also expressed per 100 population of women. The effects of the characteristics of the women of the abnormal pap smear finding was determined using the logistic regression model where 95% confidence interval and adjusted odds were used as point and interval estimates respectively while a probability value of < 0.05 was considered statistically significant. Results: A total of 949 women with HIV participated in the cervical screening program with mean age 43.3 ± 8.1 years. Abnormal smear findings were observed among 183 (19.3%: 19 cases per 100 women) with ASCUS, ASC-H, LSIL, HSIL, HSIL with suspicion of invasion and AGUS accounting for 96 (10.1%), 50(5.3%), 27 (2.9%), 6 (0.6%), 2 (0.2%) and 2(0.2%) respectively. Of the abnormal smear findings, 125 (68.3%) were adjudged to have mild cytological feature while the complementing proportion adjudged to have severe cytological features. Unadjusted odds of abnormal Pap smear result was associated with increasing age, OR 1.15(95% CI 1.127, 1.186; p = 0.001); parity, OR1.08 (95% CI 1.019, 1.141; p = 0.009). In the adjusted model, increasing age remained the only factor predicting abnormal Pap smear finding. Conclusion: Prevalence of abnormal Pap smear results remains high in HIV- infected women and is associated with increasing age. Advocacy to institutionalize screening at earlier age is therefore key to improving dismal outcomes.
Aims: This study aims to document the age, sex and site distribution of fibrous dysplasia in our tertiary health care facility in order to compare our findings with published literature. Study Design: This is a hospital-based retrospective and descriptive study extending from 1st January 2005 to 31st December 2019. Place and Duration of Study: Department of Histopathology, Jos University Teaching Hospital, Jos, Plateau State in North-Central Nigeria between 1st January 2005 to 31st December 2019. Materials and Methods: Materials consisted of Archival slides, paraffin wax tissue blocks, surgical pathology register and case files of all cases of fibrous dysplasia diagnosed histologically during the period of review. The age, sex and site affected by the tumour were documented for each case using both electronic and hard copy records. The histology slides were examined to confirm the diagnosis. A total of 165 primary bone tumours (103 benign and 63 malignant) were recorded during the period of review, of which 28 were fibrous dysplasia. Results: There were 28 cases of fibrous dysplasia which represented 17% of the primary bone tumours and 27% of the benign bone tumours. A half (50%) of the cases occurred in the second decade and 82.1% of cases were diagnosed in craniofacial bones. There was no sex bias in diagnosis. Conclusion: Fibrous dysplasia is a relatively common bone tumour in our environment. The sex distribution, age at diagnosis, and bones affected is in keeping with findings by authors from other parts of the world.
Introduction/Aim: There is scanty detailed published literature on meningiomas in Nigeria and other parts of Africa. This study is aimed at exploring the demographics, histopathology and presenting symptoms/signs of meningioma in our tertiary health facility and comparing it with other published literature. Methodology: This is a hospital based retrospective study of all histopathologically diagnosed meningioma cases at the department of histopathology of the Jos University Teaching Hospital in plateau state North-Central Nigeria. The period of review is between the 1st of January 2012 to the 31st of December 2020. Materials utilized for this research consisted of Archival histopathology glass slides, paraffin wax tissue blocks, electronic surgical pathology result data base, electronic cancer registry entries and hard copies of patient case files. The age, sex, intracranial location, histomorphological variant, grade and presenting symptom/sign was documented for all cases and analyzed. Results: Thirty-four (34) cases of meningioma out of 87 primary intracranial neoplasms were histopathologically diagnosed over the 9 years of review. There was a female predominance, with a M:F of 1:1.61. The peak age of diagnoses occurred in the 5 th and 6 th decades for females and males respectively. The commonest histomorphological variant was the Meningothelial type with the commonest intracranial site of diagnosis being the convexities. The most frequently occurring presenting symptom/sign were headache, seizures and visual impairment. Conclusion: Meningioma is the commonest intracranial tumour diagnosed at the Jos University teaching Hospital, In North central Nigeria. This tumour occurs at a relatively younger age in our environment. The sex distribution, variants, grades and symptoms/signs of this tumour in our study conforms to what is obtainable in other parts of the world.
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