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Highlights d T cell clusters are communication hubs for coordination of population dynamics d T cells can regulate their own population dynamics akin to quorum regulation d T cell quorum regulation incorporates two nested antagonistic feedback circuits d Loop dominance of feedback circuits is controlled by local T cell density
Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection Graphical abstract Highlights d Adaptive-like NK cell responses to MCMV encompass conventional and ILC1-like lineages d ILC1-like NK cells show enhanced cytokine production and splenic residency d ILC1-like NK cells show EOMES expression, target-specific cytotoxicity, and clonal expansion d ILC1-like NK cells drive cDC1 clustering and CD8 + T cell priming dependent on Ly49H and Batf3
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