No abstract

No abstract

In this study, we have investigated the thermal and hydrothermal stability of a dual mesostructured silica and of a macro-mesoporous silica. Concerning the thermal stability, results obtained by SAXS, nitrogen adsorption-desorption analysis and infrared spectroscopy show that, the macro-mesoporous material is stable up to 550°C, the mesostructure being only slightly damaged, but a contraction of both the macropores and the mesopores is observed upon calcination. Considering the dual mesoporous silica, regardless the calcination temperature, the matrix with small pores is completely degraded whereas the one with the larger pores is only weakly damaged. With regard to hydrothermal stability, all the investigated hierarchical porous silica are damaged when they are plunged into [a]

A new nanocarrier for loading and releasing drugs is reported, and ketoprofen was used as a model drug. More precisely, the carrier is a hybrid material prepared by combining oil-in-water (O/W) nanoemulsions, into which the drug has been solubilized, with mesostructured silica. This organic-inorganic hybrid material shows a controlled release of the drug that is pH dependent. If the drug is impregnated into the bare hierarchical meso-/macroporous dual silica material, obtained after the removal of the organic components by extraction, only 8 wt.-% of ketoprofen is released in a phosphate buffer medium [a]

No abstract