Highlights
Chest x-ray had a 89 % sensitivity detecting COVID-19 pneumonia during pandemic peak.
Experienced radiologists had higher specificity than less-experienced ones.
Overall and per-group sensitivity in detecting COVID-19 pneumonia increased over time.
Overall and per-group accuracy in detecting COVID-19 pneumonia increased over time.
Leiomyosarcoma of the lung is a type of tumour rarely found in childhood. It arises from smooth muscle either of bronchial or arterial walls, has a variable pattern of local growth, blood-borne metastatic spread with lymph nodes sparing and a clinical course characterized by fever, cough and worsening dyspnea. We report a case which occurred in a 14-year-old girl, reviewing all the other cases found in the literature.Primary leiomyosarcoma of the lung is a malignant tumour occurring rarely both in children [2-5, 6, 8, 9, 11] and adults [1, 2, 7, 10].The tumour arises from smooth muscle either of the bronchial or arterial walls and is characterised by a variable pattern of local growth and blood-borne metastatic spread, while lymphatics and lymph nodes are usually spared [2,7,10].
The incorporation of responsive elements into photonic
crystals
is an effective strategy for fabricating active optical components
to be used as sensors, actuators, and modulators. In particular, the
combination of simple multilayered dielectric mirrors with optically
responsive plasmonic materials has proven to be successful. Recently,
Tamm plasmon (TP) modes have emerged as powerful tools for these purposes.
These modes arise at the interface between a distributed Bragg reflector
(DBR) and a plasmonic layer and can be excited at a normal incidence
angle. Although the TP field is located usually at the DBR/metal interface,
recent studies have demonstrated that nanoscale corrugation of the
metal layer permits access to the TP mode from outside, thus opening
exciting perspectives for many real-life applications. In this study,
we show that the TP resonance obtained by capping a DBR with a nanostructured
layer of silver is responsive to Escherichia coli. Our data indicate that the modification of the TP mode originates
from the well-known capability of silver to interact with bacteria,
within a process in which the release of Ag+ ions leaves
an excess of negative charge in the metal lattice. Finally, we exploited
this effect to devise a case study in which we optically differentiated
between the presence of proliferative and nonproliferative bacteria
using the TP resonance as a read-out. These findings make these devices
promising all-optical probes for bacterial metabolic activity, including
their response to external stressors.
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