[Purpose] There are many types of hyaluronic acid preparations, but no clear data are available about which preparations is more effective. The aim of this trial was to investigate the effectiveness of different types of hyaluronic acid preparations on pain and function of inpatients with knee osteoarthritis. [Subjects and Methods] All patients were diagnosed by clinical examination and x-ray. Ostenil PLUS® was injected into 28 patients (group 1, 1.6 million daltons), and MONOVISC® (group 2, 2.5 million daltons) was injected into 46 patients. Demographic data and Western Ontario and McMaster Universities Osteoarthritis Index and Visual Analog Scale scores were used for clinical evaluation at 1, 3, and 6 months post injection. [Results] In both groups, baseline Ontario and McMaster Universities Osteoarthritis Index and Visual Analog Scale scores were higher compared with those in subsequent evaluations. Based on the pre- and post-injection data, a significant reduction in all scores was observed after the injections for in both groups. According to intergroup comparisons, there was no significant difference in any of the scores between the two groups. [Conclusion] There were no difference in Ontario and McMaster Universities Osteoarthritis Index and Visual Analog Scale scores in patients with knee osteoarthritis injected with two different hyaluronic acid structures in short-term preparations.

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Considering the potential side effects of corticosteroid, lidocaine injection is a good alternative treatment of carpal tunnel syndrome instead of corticosteroids.

Background One-third radius (33% radius) bone mineral density (BMD) measurements of the non-dominant forearm using dual-energy X-ray absorptiometry (DXA) may be used for the diagnosis of osteoporosis in certain circumstances. Objectives The aim of this study was to investigate the ability of radial speed of sound (SOS) measurements for identifying osteoporosis at the radius as measured by DXA. Methods Both 1/3 radius BMD and SOS of the non-dominant forearm were measured in 128 women aged between 21 and 79 years using DXA (Hologic QDR® 4000) and a multi-site quantitative ultrasound (QUS) device (Sunlight Omnisense™ 8000), respectively. Osteoporosis at the radius was defined according to the WHO criteria (a T-score ≤-2.5) in postmenopausal women in the sample studied. In premenopausal women, Z-scores of ≤-2.0 were used for defining osteoporosis or BMD below the expected range for age. Results Pearson correlation coefficients revealed statistically significant correlations between DXA 1/3 radius BMD and radial SOS measurements (r=0.496; p<0.001) as well as 1/3 radius and radial SOS T-scores (r=0.495; p<0.001). The areas under the receiver operating characteristic curves (AUCs) for radial SOS and its T-score for predicting osteoporosis or BMD below the expected range were 0.762 (p<0.001) and 0.760 (p<0.001), respectively. Conclusions Significant correlations between radial BMD measurements and QUS parameters and fair AUCs for QUS parameters for identifying osteoporosis or BMD below the expected range found in this small sample of women may have implications that radial SOS measurements may provide valuable information for treatment decisions when DXA cannot be done in any region of interest. Disclosure of Interest None Declared

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