This study confirms that tranexamic acid is effective in reducing intrapartum and postpartum bleeding in patients giving birth by cesarean section. Although some obstetricians are still worried about its thrombosis risk, our study shows that it can be used safely in aforementioned patients.
Contrast-induced nephropathy (CIN) is a prevalent and serious complication after primary percutaneous coronary intervention (pPCI). Although the association between serum osmolarity and chronic kidney disease is well established, its relation to CIN in patients with ST-segment elevation myocardial infarction (STEMI) undergoing pPCI needs to be elucidated. We evaluated the predictive value of serum osmolarity for CIN development in patients with STEMI (n = 768) undergoing pPCI. Serum osmolarity on admission was calculated. The study population was divided into 2 groups according to CIN development, and both groups were compared according to clinical, laboratory, and demographic features, including the serum osmolarity. Serum osmolarity was significantly higher in patients with CIN than in those without CIN (278 [8] vs 284 [9]; P = .024). Serum osmolarity (odds ratio: 1.052; 95% confidence interval: 1.018-1.086; P = .002), hemoglobin, contrast media volume, creatinine on admission, basal SYNergy between PCI with TAXus and cardiac surgery II score, and left ventricular ejection fraction were found to be independent predictors of CIN. Serum osmolarity (given the simple calculation of this parameter on admission) can be useful to define patients with STEMI undergoing pPCI who are more likely to develop CIN.
We report on two unusual clinical presentations of broad-ligament leiomyomas. The first case was a combination of broad-ligament leiomyoma and ectopic gestational sac at the same location. The other case was a broad-ligament leiomyoma presenting as an ovarian malignancy. The differential diagnosis of broad-ligament leiomyoma should be considered in cases of an adnexal mass. Additionally, a broad-ligament leiomyoma could be the reason for an ectopic pregnancy.
NT-proBNP (5042.1±1626 versus 1417.1±1711.6 pg/ml) and TN-C (1089±348.6 versus 758.5±423.9 ng/ml) levels were significantly higher in the malignant arrhythmia group than that of the benign arrhythmia group (p.
Significance of the Study• The left atrial volume index is a predictor of increased cardiovascular risk in hemodialysis patients. • This study demonstrates an association between the P wave peak time and the echocardiographically measured left atrial volume index. • Measuring the P wave peak time duration with an electrocardiogram could help identify high-risk hemodialysis patients with increased left atrial volume indexes.
AbstractObjective: An increased left atrial volume index (LAVI) is related to increased mortality in hemodialysis patients. In the present study, we evaluated the association between the LAVI and the P wave peak time (PWPT), a newly introduced electrocardiographic parameter, in hemodialysis patients.
Methods:The study population was made up of 79 hemodialysis patients with a mean age of 53 ± 18 years (55.7% were males). These patients were divided into a normal LAVI (≤28 mL/m 2 ) group (n = 45) and an increased LAVI (> 28 mL/m 2 ) group (n = 34). The demographic, clinical, laboratory, echocardiographic, and electrocardiographic variables of the groups were compared. Results: The P wave terminal force from lead V1, P wave dispersion and PWPTs obtained from leads V1 and D2 (PWPT D2 ) were significantly higher in the patients with increased LAVIs. In multivariable analysis, only the PWPT D2 was an independent predictor of an increased LAVI (odds ratio = 1.117, 95% CI = 1.052-1.185, p < 0.001).The receiver-operating characteristic curve analysis showed that the best PWPT D2 cutoff value for predicting an increased LAVI was 60 ms, with a sensitivity of 76.5% and a specificity of 66.7% (area under the curve = 0.736, 95% CI = 0.625-0.829, p < 0.001). Conclusion: This study showed that a prolonged PWPT D2 was independently associated with an increased LAVI in hemodialysis patients. Therefore, measuring the PWPT D2 duration on an electrocardiogram may help define high-risk hemodialysis patients with increased LAVIs.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.