This study raises the issues of occupational risks and the new approaches to their assessment, improving research methods in this direction. The relevance of the stated subject is due to a wide variety of situations that arise in modern industries and have a high degree of risk for employees of enterprises. The purpose of this study is to determine new approaches to occupational risk assessment, as well as to study various aspects of improving production activities in the context of using new methods for assessing the degree of risks. The leading scientific method is a combination of analytical and logical approaches to the set of issues brought into the topic of this study. The main results of this study: identification of new, effective methods for assessing the degree of risks of occupational injuries and estimation of the level of occupational injuries at Ukrainian enterprises in 2020 and several previous years. Prospects for further study in this direction introduce methods for assessing the real level of occupational risks in the production sphere, in order to reduce the total number of situations associated with risk for workers of modern industrial enterprises that arise in the process of conducting work activities. The applied value of this study lies in the possibility of the subsequent practical application of the obtained results, in order to form the basis for the safe implementation of professional activities by employees of enterprises and organizations operating in various spheres of the economy, industry, and production. Identification of various aspects of occupational risks assessment in various areas contributes to the elimination of such risks and prevents their occurrence in the future.