Medical news of north caucasus 2015. Vоl. 10. iss. 2 137 tween patients with BMI over or less than 50. Despite low number of participants, we suppose that increasing of the study power will be not able to find differences between groups. Basing on this results, we may also suppose that undifferentiated (on the basis of BMI) implementation of the enhanced recovery protocols does not carry risk increase for postoperative complications or complication severity in patients with high or extremely high BMI. However, early humoral mechanisms of action of bariatric surgery limit the study results to the bariatric patients, and the results of enhanced recovery protocols implementation in extremely obese patients in non-bariatric surgery may differ and should be additionally studied.