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BACKGROUNDDiabetes is the most common non-communicable disease globally. Awareness of mucocutaneous manifestations may lead to recognition of yet undiagnosed DM. MATERIALS AND METHODSIt is a descriptive and observational study conducted on 75 diabetic patients. Investigations performed included urine for sugar, protein, fasting and post prandial blood sugar, blood urea, serum creatinine, lipid profile, liver function test and ECG. Special investigations like culture and sensitivity of pus, skin scrapings for fungal infections and biopsy of skin lesion was done in selected cases. Analysis was carried out using SPSS 10. RESULTSOf 75 patients examined, 60 patients (80%) suffered from cutaneous lesions. Some patients suffered from more than one lesion; 50% of total cases suffered from infections. Diabetic dermopathy in our study was observed in 20% of the patients. Some of the cutaneous markers of diabetes mellitus like necrobiosis lipoidica diabeticorum, diabetic bullae, acquired perforating dermatosis and stiff skin syndrome is not seen in our study. CONCLUSIONThis study was done to highlight the importance of association of cutaneous lesions and diabetes mellitus. KEYWORDS BACKGROUNDDiabetes is the most common non-communicable disease globally. It is estimated that nearly 380 million adults worldwide will have diabetes by 2025. Diabetes among adults has reached approximately 20% in urban populations and 10% in rural population. It may be due to genetic defect, autoimmunity, defect in the formation of insulin or decreased insulin sensitivity. It may occur at any age, but greatest number of individuals with Diabetes was aged 45 -64 yrs. 1 DM increases with ageing. Prevalence is slightly greater in men than female. Risk factors are changes in lifestyle like diet, lack of dietary fibres, sedentary lifestyle, alcohol and stress. 2 The cutaneous signs are the manifestations of multiple factors. Abnormal carbohydrate metabolism, other altered metabolic pathways, atherosclerosis, microangiopathy, neuronal degeneration and impaired host mechanism all play an important role. 3 Cutaneous involvement has been found in 43% -66% of diabetic patients approximately. 3 This study was done to highlight the importance of association of cutaneous lesions and diabetes mellitus.

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