Depth of invasion (DOI) and tumour thickness (TT) are known prognostic indicators in oral squamous cell carcinoma (OSCC), but varying definitions have been used by pathologists for reporting. The American Joint Committee on Cancer (AJCC) has proposed adoption of a uniform definition of DOI and incorporated this measurement in the revised TNM staging (8th edition); however, unambiguous DOI determination can be a challenge in clinical practice. We reviewed archived slides of 95 cases of T1/T2N0 OSCC and listed the challenges in accurate DOI measurement with pictographical documentation. The impacts of DOI and TT on disease-free survival (DFS) were also assessed. The mean DOI and TT was 5.89 mm and 7.32 mm respectively. Challenge in horizon estimation for DOI measurement was experienced in 75/95 cases (78.9%). The most common challenges were lack of adjacent uninvolved mucosa in sections or presence only on one side, rounded/ convoluted nature of the tumour surface for tongue and polypoidal tumours, and angulation of adjacent mucosa for alveolar or lip tumours. In cases with very thin epithelium, DOI was equal to TT. In spite of the challenges, Kaplan-Meier analysis showed DOI > 5 mm significantly predicted poorer DFS while TT did not. We recommend various guidelines to help improve consistency in measuring DOI and recording of TT in ambiguous cases for accurate staging of OSCC.

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Background: Fallopian tube is a common specimen in the laboratory. It is affected by a wide spectrum of diseases but there are only occasional studies, documenting histological changes in the fallopian tube removed for all reasons. Aims and objectives:To study the gross and microscopic features of the excised fallopian tubes and to study the common and unusual lesions in them. To find the incidences of tumour and the tumour like lesions of the fallopian tube. Materials and Methods: A sample size of 200 cases was included in this study which consisted of all the specimens of fallopian tubes of all age groups obtained by salpingectomy, tubal ligation, salpingooophorectomy or along with hysterectomy. All the specimens were processed by routine histopathological techniques. Histopathological features were studied on hematoxylin and eosin stained sections. Results: In our study, majority of the cases belonged to age group of less than or equal to 30 years. Total number of 372 fallopian tubes were received from 200 patients. Out of the 372 fallopian tube specimens, 248 (66.67%) were normal whereas 124 (33.33%) fallopian tubes were abnormal. Of the 124 abnormal fallopian tube specimens, majority were diagnosed to have non neoplastic lesions that is 119 (95.97%) fallopian tubes, and 5 (4.03%) were diagnosed to have neoplastic lesions. The most common histopathological finding observed were inflammatory conditions seen in 47 (12.63%) of the fallopian tubes seen most commonly in the age group of less than or equal to 30 years. Conclusion: The present study describes the broad spectrum of lesions in fallopian tube and their incidence with respect to age group. Majority of the lesions were non neoplastic comprising predominantly of inflammatory lesions, seen most commonly in younger age group. Neoplastic lesions of the fallopian tube were rare.

Context: Lung cancer is the most common cancer affecting males worldwide. Its incidence in females is also on an increasing trend. Other conditions affecting lung-like tuberculosis are on a rise in middle-east countries due to overcrowding and poor living conditions. In developing countries, image-guided fine-needle aspiration cytology (FNAC) of lung lesions is a cost-effective method for early detection and apt treatment of patients by physicians. Aim: The main aim of this study is to identify the importance of computed tomography (CT)guided FNAC as an accurate and cost-effective tool in early diagnosis of lung lesions. Settings and Design: It was prospective and retrospective study done in a government medical college of West Bengal, India. Material and Methods: Over a period of two years, 42 cases were included in the study. These were further subjected to evaluation of pulmonary mass lesions by CT guided transthoracic fine needle aspiration cytology. Results: Out of these 42 cases majority were males with cough being most common clinical presentation. On CT guided FNAC of pulmonary lesions 69% of cases were malignant. Cytoradiological correlation in this study was 90.4%. Conclusion: CT guided FNAC of lung lesions is an accurate, cost effective and quick technique for early diagnosis, referral and appropriate treatment of patients in developing countries.

Co-existence of mucinous cystadenocarcinoma with mature cystic teratoma in the same ovary is very rare. We report a case in a 48-year-old female who presented with left abdominal mass. CT scan revealed a heterogeneous enhancing left ovarian mass lesion. Clinical diagnosis of complex ovarian cyst was made, later underwent laparotomy and histologically diagnosed as mucinous cystadenocarcinoma (grade 2) co-existing with benign cystic teratoma, stage Ia (FIGO) of the left ovary. Six months after surgery, the patient is doing well without any recurrence or metastasis. Hence, histopathological examination plays a significant role in accurate diagnosis and management of the patient. So, we should be aware of these rare co-existent tumours and meticulous dissection should be done to look for any synchronous tumours or malignant areas; since management and prognosis will vary significantly depending upon the microscopic type and stage.