An efficient synthesis of various 3-fluorochromones (3-fluoro-4H-chromene-4-ones) from enamino ketones by using Selectfluor is described. The key step in the synthesis involves tandem fluorination and cyclization to form 3-fluorochromones in good yields. The significant features of this method include simple operational procedures, a high purity of the product, and excellent regioselectivity.

An efficient and facile synthesis of various 3-trifluoromethyl-chromones via enamino ketone is de-scribed. The key step in the synthesis involves introduction of trifluoromethyl (CF3) moiety on chromone structure. The significant features of this method include simple opera-tional procedure, high purity and yield of the product and excellent regio-selectivity.