Introduction: Double chambered ventricle is a rare congenital cardiac anomaly, where the ventricular chamber is wholly or partially partitioned usually by abnormal muscular ridges. Double chambered right ventricle (DCRV) is more common than double chambered left ventricle (DCLV). Methods: A retrospective observational morphological study of 31 autopsied hearts during a 16-year period highlighted the varied clinical presentations of this pathology and the associated per-operative problems.Results: DCRV was found to exist not only with simple cardiac pathologies such as ventricular septal defect and tetralogy of Fallot, but also more complex pathologies such as transposition of great arteries, double outlet right ventricle, left atrial isomerism, and Ebsteins anomaly of tricuspid valve. Double chambered left ventricle in our series was an associated asymptomatic anomaly. Conclusions: Closure of the ventricular septal defect may result in isolated DCRV causing proximal right ventricular (RV) hypertension. Postoperative RV dysfunction may compound the ill effects of missed DCRV, RV hypertension and pulmonary hypertension, if any. Double chambered left ventricle may present as an associated asymptomatic anomaly. (Ind J Thorac Cardiovasc Surg 2007; 23: 135-140)