Juxtaglomerular cell tumor is a rare renal neoplasm with fewer than 100 cases reported in literature, of which 7 cases were diagnosed during pregnancy. This tumor is generally seen in young adults with female preponderance. Patients generally present with hypertension, hyperaldosteronism, and hypokalemia secondary to renin secretion by the tumor cells. When the tumor occurs during pregnancy, the hypertension is often presumed to be pregnancy-induced hypertension and results in fetal loss. We report the case of a 21-year-old woman who presented with hypertension in the first trimester of pregnancy, which was attributed to and treated as pregnancy-induced hypertension. Routine ultrasonography of abdomen in the fourth month revealed a right renal mass. Patient underwent preterm delivery in the seventh month, and the infant did not survive, and subsequently after 1 month, a partial nephrectomy was performed. The diagnosis of juxtaglomerular cell tumor was confirmed by light microscopy. The tumor was positive for CD34 and vimentin. Electron microscopy showed the characteristic rhomboid renin granules in the cytoplasm of the tumor cells.

Malakoplakia is a granulomatous inflammatory condition commonly involving the urogenital tract. Principally it involves the urinary bladder, prostate is a rare site. Clinical and radiological examination sometimes mimics malignancy. Histology remains confirmatory modality for the diagnosis. Hereby we report a case of prostatic malakoplakia in an elderly male who presented with lower urinary tract symptoms in the past fifteen days. Urine routine microscopy showed pus cells; culture report was positive for E. coli. Serum Prostate Specific antigen (PSA) was 4.6 ug/ml. Magnetic Resonance Imaging (MRI) showed a bulky prostate. A 12-core biopsy was done to rule out malignancy and the histopathology showed benign prostatic glands and the stroma with a predominant population of epithelioid histiocytes and the characteristic Michealis-Gutmann bodies. After a course of antibiotic Nitrofurantoin, transrectal ultrasound was repeated which showed reduction in the prostatic volume. Subsequently Trans-Urethral Resection of Prostate (TURP) was done to relieve the persistent lower urinary tract symptoms. Histology showed similar features. Special stains -Von kossa and Prussian Blue highlighted the Michealis-Gutmann bodies.