Anemia is a common symptom of haematological disorders in people of all ages .The spectrum of haematological disorders differs significantly between developing and industrialized countries. The primary use of bone marrow aspirate is for cytological examination. It enables study into the cellularity of the bone marrow as a whole, the detection of specific lesions, and the amount of infiltration by various disease entities. The aim of the stud Aims & objective: y is to evaluate the spectrum of haematological disorders reported in bone marrow aspiration and to know the age and sex incidence. This prospective study is an observational study was conducted over a one-year Materials and methods: period on 73 patients and the spectrum of hematological disorders was studied on bone marrow aspiration smears. Conclusion: A thorough examination of the bone marrow is essential for diagnosing haematologic disorders. It is a simple and cost effective procedure which can be performed routinely without using any specialized equipment or a need of general anaesthesia

Introduction: Leukemias are neoplastic proliferations of haematopoietic stem cells and form a major proportion of haematopoietic neoplasms that are diagnosed worldwide. Typing of leukemia is essential for effective therapy because prognosis and survival rate are different for each type and sub-type Aims: this study was carried out to determine the frequency of acute and chronic leukemias and to evaluate their clinicopathological features. Methods: It was a hospital based cross sectional study of 60 patients carried out in the department of Pathology, JMCH, Assam over a period of one year between February 2018 and January 2019. Diagnosis was based on peripheral blood count, peripheral blood smear and bone marrow examination (as on when available marrow sample) for morphology along with cytochemical study whenever possible. Results: In the present study, commonest leukemia was Acute myeloid leukemia (AML, 50%) followed by Acute lymphoblastic leukemia (ALL 26.6%), chronic myeloid leukemia (CML, 16.7%) and chronic lymphocytic leukemia (CLL, 6.7%). Out of total 60 cases, 36 were male and 24 were female with Male:Female ratio of 1.5:1. Acute lymphoblastic leukemia was the most common type of leukemia in the children and adolescents. Acute Myeloid leukemia was more prevalent in adults. Peripheral blood smear and bone Conclusion: marrow aspiration study still remains the important tool along with cytochemistry, immunophenotyping and cytogenetic study in the diagnosis and management of leukemia.

Background: Bone marrow aspiration and bone marrow trephine biopsy are the two procedures done for the diagnosis of both hematological and non-hematological disorders and are complimentary to each other. To studyAim and Objective: the essential haematological evaluation of cases where bone marrow aspiration and bone marrow biopsy is indicated and to correlate the ndings of bone marrow aspiration and bone marrow biopsy in diagnosing various haematological disorders. The study wasMaterial and Methods: done on 86 patients in the age group 10-80 years. All had undergone simultaneous bone marrow aspiration and bone marrow biopsy procedures in the department of Clinical Haematology in a tertiary hospital. Standard methods were followed for bone marrow aspiration and biopsy procedure and for staining and evaluation of cellular aspirate. The Male to Female ratio of 1.4:1; 60% of patients belonged to 20-Observation & Results: 60years group. Bone marrow and aspiration yield high diagnostic evaluation in megaloblastic anaemia (89.47%) against aspirates (10.52%) with p value of 0.00086 while in aplastc anaemia the aspirate evaluation shows better diagnostic yield (p value of 0.285). A combinationConclusion: of bone marrow aspiration and bone marrow biopsy give a better morphology of the cells and with good picture of the architecture and pattern of distribution of the cells. There is high diagnostic yield in evaluation of anemia.