A prospective study was conducted in 25 consecutive patients of paranasal sinus aspergillosis to categorize and treat them based on a fixed treatment protocol. The three types of aspergillosis categorized as per definitive criteria were chronic invasive (six), non-invasive (fungus ball) (seven) and non-invasive destructive (12). Adjuvant chemotherapy was employed in non-invasive destructive and chronic invasive disease. Ketoconazole was used in the first variety and itroconazole in the latter. Only two patients had recurrence after a mean follow-up of 11 months (range: 6-20 months). They belonged to the non-invasive destructive category and the recurrence had progressed to invasive variety. It is suggested that non-invasive destructive disease should be followed up regularly with endoscopic examination, CT and fungal serology to detect recurrence. Categorization of the paranasal sinus aspergillosis helps to institute proper treatment. Adjuvant chemotherapy in the form of ketoconazole along with surgery is effective in non-invasive destructive disease to prevent recurrence and progression to invasive disease. Chronic invasive disease with its propensity to involve orbit and intracranial cavity should be managed at the earliest with surgery and itraconazole.
Introduction: This case report illustrates complex sigmoid diverticulitis presenting as tubo-ovarian abscess and developed iliopsoas abscess as complications. Case description: A 37-year-old female presented with lower abdominal pain, fever and diarrhoea. Initial clinical assessment and CT imaging diagnosed tubo-ovarian abscess. She underwent laparoscopic drainage. Patient represented with similar complaints. Further imaging visualised persistent tubo-ovarian abscess with a new iliopsoasabscess. Her disease progression and initial treatment failure led to clinical diagnosis of sigmoid diverticulitis. The patient underwent Hartmann's procedure and radiological drainage and has been asymptomatic since then. A Hartmann reversal is planned. Discussion and Conclusion: First, it demonstrates the potential for sigmoid diverticulitis to present as tuboovarian abscess and develop iliopsoas-abscess complications. Second, it signifies prudence of high degree suspicion when evaluating female patients with pelvic abscesses and gastrointestinal symptoms. Finally, it shows the value of the MDT-approach in providing optimal care.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.