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In urban areas, especially in adolescents, there is an increasing trend to engage in activities, which are not in compliance with circadian clock and natural rhythm of light dark circle, turning them into a night owl chronotype. Research evidences highlight various health issues as a result of this chronotype. There are no research evidences of whether change of this night owl chronotype to lark shall correct these health issues. This is a unique case of a young unmarried lady, aged 22 years, from Lucknow, India, who visited OPD of Regional Ayurveda Research Institute for Eye Disorders (RARIED), Lucknow, with complaints of scanty menstrual flow along with hormonal imbalance, which had no improvement even after 6-7 months of medication. On probing the cause of these complaints, it was found that the patient had a night owl chronotype since past few years along with untimely food habits. The patient was then counseled for shifting the chronotype to lark along with timely food habits, which is in compliance with Ayurveda Guidelines of Lifestyle (AGOL) without any medications. After that a remarkable improvement in menstrual health was observed. Menstrual flow reached back almost to normal and the hormonal profile was balanced, with an exception to anti-mullerian hormone (AMH), which had only a slight improvement.

Background: Conjunctivitis is a common condition of the eye that occurs worldwide and affects all ages and social strata, affecting more than 2% of the population. Conventional treatment has many options for treating the disease. Despite adequate treatment options, patients continue to suffer troublesome symptoms. Complementary and alternative medicine (CAM) therapies may play a significant role here. Systematic reviews on this topic have been published for herbal medicines. Data are available on plenty of studies individually proving efficacy and safety of various Shodhana, Shamana, and Netra Kriyakalpa in conjunctivitis. However, systematic review of Ayurveda interventions for conjunctivitis is unavailable. This study aims at a thorough review of published clinical data of safety and efficacy of Ayurvedic interventions in the management of conjunctivitis. Materials and methods: A systematic review of randomized controlled trials (RCTs), quasi-randomized controlled trials (QRCTs), controlled clinical trials (CCTs), and multiple arms clinical trials on conjunctivitis published till date will be conducted. Studies having patients fulfilling the diagnostic criteria based on the symptomatology of Abhishyanda (HF-1) explained in classic Ayurveda texts and conjunctivitis of all ages and either sex will be included. Studies in which Ayurvedic treatments (Shamana, Shodhana, or/and Netra Kriyakalpa) with any dose, type, schedule, drug, dosage form, and advised Pathayapathya (lifestyle changes) as intervention or control will be selected. The primary outcome will be the response to treatment and onset of serious adverse events. Ethics and dissemination: Formal ethical approval will be obtained. The results will be disseminated through a peer-reviewed publication. Trial registration number: International prospective register for systematic reviews (PROSPERO) number CRD42019129436.

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