ABSTRACT-A prospective case study of patients presenting with clinically suspected keratitis was conducted at Al-Rehma Hospital, Sirte, Libya between January 2008 and November 2010. A total of 32.9% patients were identified with fungal keratitis, Aspergillus and Fusarium together accounted for 89.28% of cases. Males had higher predisposition as compared with females. Trauma (78.5%) was the major cause, vegetative injury alone constituting 60.7% of cases. Other most common identifiable risk factors were history of diabetes mellitus (17.8%), contact lens (21.4%) and corticosteroids (3.57%). Fungal keratitis still possesses a significant threat for increased ocular morbidity. The overall knowledge of fungal keratitis with its clinical determinants and risk factors, would aid in general awareness and prevention of complications associated with it.

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