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Background: Urinary tract infection (UTI) is one of the most frequently encountered problems owing tosigniÞ cant number of patients needing hospitalization during pregnancy. The incidence of UTI in pregnantwomen is reported to be high up to 7-8%.Methods: This is a prospective study conducted in Valley Maternity Hospital during a period of 6 months(Jan 2011 to June 2011). 520 MSU (Mid stream urine samples) from pregnant women clinically suspected ofurine infection were evaluated by urine dipstick analysis, microscopic and culture method. The isolates wereidentiÞ ed and antibiotic sensitivity pattern was determined by standard protocol.Results: The majority of the patients were in-between the age group of 20-30years- 338cases (65%) and thesepatients usually presented in the Þ rst trimester of pregnancy- 317cases (60.96%). Out of the 520 clinicallysuspected UTI cases, 232 (44.61%) was culture positive. Out of the culture positive cases; Escherichia coli(E.coli) was the most common accounting for a total of 144cases (80%). Nitrofurantoin was found to be the mosteffective drug against the gram negative (Gm-ve) bacteria. Similarly, Ampicillin, Amoxycillin and Cloxacillinwere found to be effective agent against gram positive (Gm+ve) bacteria.Conclusion: Screening for bacteriuria is recommended among all pregnant women at the Þ rst prenatal visit andin the subsequent trimesters of pregnancy.Key words: UTI, Pregnant women, Antibiotics, Culture method.Prevalence of Metabolic Syndrome and its Component inPatients with Acute Coronary Syndrome.Conclusions: Metabolic syndrome is most common and important risk factor in patients of coronary arterydisease. Other risk factors like smoking, obesity, dyslipidemia, hypertension and diabetes were also frequentlyfound. Public awareness to control the risk factors can reduce the prevalence of coronary artery disease in ourcountry.doi: http://dx.doi.org/10.3126/mjsbh.v12i2.12928

003 AbstractPurpose: To compare central corneal thickness (CCT) among glaucoma patients, glaucoma suspects, and normal subjects and to determine its association with glaucoma severity in Nepalese population. Methods:This study included 400 eyes (149 glaucoma, 157 glaucoma suspects, 94 controls) of 400 participants examined in a glaucoma clinic and eye OPD in Nepal. CCT was measured by ultrasonic pachymetry. Results:CCT was significantly different among the study groups (P = 0.05), with the thinnest CCT in normal tension glaucoma (NTG) and thickest in ocular hypertension (OHT). CCT (in µm) was thinner in NTG (519.6 ± 31.6; P = 0.06) and primary open angle glaucoma (POAG) (524.5 ± 35.8; P = 0.026) than controls (536.6 ± 28.9); and it was thinner in POAG compared to primary angle closure glaucoma (PACG) (541.3 ± 50.5; P = 0.028) and OHT (559.8 ± 28.1; P = 0.017). In NTG, CCT was thinner compared to Glaucoma suspects (GS) (531.6 ± 35.0; P = 0.038), PACG (P = 0.008), and OHT (P = 0.008).There was no correlation between CCT and visual field defect and CCT was not statistically different between early, moderate and severe POAG groups. Conclusions:We report that CCT in glaucoma suspects is similar to normal subjects and POAG, but thicker than NTG. These data will be important in clinically monitoring glaucoma suspects that are at increased risk of glaucoma. Our results may be population specific and further longitudinal studies are warranted to determine influence of CCT on glaucoma progression in this population.

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