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This is a case study of 32 year old Mrs. M, a case of Young Onset Parkinson's Disease (YOPD) with hypothyroidism. With informed consent, Mrs. M was selected for the case report because Young Onset Parkinson’s Disease is a rare diagnosis. She was assessed using MDS-UPDRS pre- and post-intervention .She was provided Occupational Therapy intervention using the Person-Environment-Occupation Model for a period of three months and has shown significant improvement in UPDRS scores. Her primary diagnosis is Young Onset Parkinson’s Disease, secondary diagnosis being hypothyroidism.The patient, being in her early 30s, many of her life roles were altered. The patient’s main concerns are that she has difficulty in performing her basic and instrumental ADLs and difficulty in caring for her loved ones. Mrs. M was treated on weekly basis for an intervention period of three months using the Person Environment Occupation Model and assessed using the Unified Parkinson’s Disease Rating Scale; pre and post treatment. She was in stage 3 of Hoehn and Yahr scale of classification of Parkinson’s Disease. Scores were assessed on Unified Parkinson’s Disease Rating Scale, pre and post three months of intervention; showed improvement in non motor and motor aspects of experiences of daily living, motor examination and motor complications. Component scores were decreased dramatically especially in the areas of anxious mood, fatigue, tremors, posture and bradykinesia which revealed that functional levels improved following intervention. Keywords: Young Onset Parkinson’s Disease, Unified Parkinson’s Disease Rating Scale, Person Environment Occupation (PEO) based Occupational Therapy Intervention, case report.

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Rationale: Chronic alcoholics suffer from cognitive impairment, thereby affecting their ADL and work performance. Objectives: The objective was to screen chronic alcoholics for cognitive impairment and assessing affectations in various components of MoCA. Early screening to help them from further deterioration in ADL and work. Materials and Methodology: In this case control study, 50 chronic alcoholics, males, age group 30–50 years, abstaining for more than two months, referred to outpatient De-addiction Occupational Therapy department of K. E. M. Hospital, Mumbai were screened using MoCA (Hindi) and compared with their age matched control group. Results: All patients showed mild cognitive impairment (MCI) on MoCA, irrespective of pattern and frequency of drinking. Their average mean score in MoCA test and control group was 21.02 and 26.03, respectively. The domains more affected were language, abstraction and memory, thus affecting their performance in ADL and work. Results were analyzed using unpaired ‘t’-test and were statistically significant at the level of p < 0.05 and 95 per cent confidence level. Conclusion: Screening of chronic alcoholics using MoCA showed MCI with varying degree of affectations in the sub-components of the test.