No abstract

Type 2 DM is a complex metabolic disorder which can have detrimental affect on all the system of the body. This is often associated with accelerated risk of dementia.Objective of the study is to assess the cognitive function in individuals with type 2 diabetes. Twenty ve type 2 diabetics attending the endocrinology outpatient department of MS Ramaiah Medical College and Hospital were recruited for the study. Twenty ve age, sex and education matched normal subjects were enrolled for the study. Detailed history was taken. A thorough general physical examination and systemic examination was done. The subjects were divided into the two groups based on their serum HbA1C level. Cognitive function was assessed using Critical Flicker Frequency (CFF) and a validated questionnaire Adenbrooke's Cognitive Examination-III (ACE-III). Statistically signicant reduction was found in CFF values between controls and type 2 diabetics. ACE III scores were also signicantly lower in type 2 diabetics compared to controls. Decrease in CFF value and ACE-III score indicates reduction in cognitive function in type 2 diabetics. Our study shows an early onset of cognitive decline in type 2 diabetics compared to normal subjects.

Pre-diabetes is a stage in which blood glucose levels are higher than normal but not high enough to call as diabetes. The aim of study was to determine the association of body mass index with pre-diabetes. A sample of 50 subjects, 25 prediabetics and 25 normal healthy individuals between the ages 20-50 years participated in our study. Anthropometric measurements, educational level and HbA1C level of participants were recorded. Statistical analysis was done using SPSS 20. All parameters were summarized using mean and standard deviation. Students t-test was used to compare mean differences in all the parameters between the two groups. A p-value ≤ 0.05 were considered significant. The mean BMI of the normal subjects and prediabetics were 23.07 ± 2.19 and 27.84 ± 1.88 Kg/m 2 respectively. Our study showed that pre-diabetic subjects had a higher BMI level compared to normal healthy subjects. Proper maintenance of body weight as per height is of utmost importance to lead a normal heathy life and controlling BMI can also prevent the progression of diabetes from prediabetes.