Labour Induction with intravaginal Misoprostol versus Oxytocin in Term PrematureRupture of Membranes. OBJECTIVES: To compare the safety and efficacy of misoprostol with oxytocin for labour induction in women with premature rupture of membranes beyond 36 weeks gestation. METHODS: 65 subjects with rupture of membranes without labour were assigned to receive. vaginally administered misoprostol 50 ug, every 4 hrs. and another 65 subjects with rupture of membranes at term received intravenous oxytocin infusion and we compared the duration of labour, intrapartum complications, mode of delivery and the maternal and neonatal outcomes in the two groups. RESULTS: Results of the 130 subjects studied, 65 received misoprostol and 65 oxytocin infusion. The average interval, from start of induction vaginal delivery was significantly shorter (660 minutes) in the misoprostol group than the oxytocin group (1105 min). Oxytocin administration was necessary in 13 (20%) subjects receiving misoprostol. There was increased incidence of tachysystole in misorpostol group 22 (33.8%) compared to the oxytocin group 9 (13.8%) No significant difference was found in the mode of delivery neonatal and maternal outcomes in the two groups. CONCLUSION: Vaginal administration of misorpostol is safe and effective alternative to oxytocin infusion for labour induction in women with premature rupture of membranes at term.

Background: 3.4 million people worldwide are estimated to be living with HIV in 2009. In 2007, only 33 percent of HIV-positive women received antiretroviral drugs to minimise the risk of infection from mother to child. Aims and Objective: To study Awareness of HIV testing in pregnant women and their husband during ANC attending in OBGY Department. Methodology: This was a cross-sectional analysis carried out over the one-year period of the ANC women attending the OBGY department. By taking the written consent included in the report, there were 108 ANC women in the one year period. By interviewing the pair, knowledge of HIV testing and HIV transmission was assessed. The responses were noted and evaluated by excel software for Windows 10 in the excel sheet. Result: In our study we have seen that the majority of the ANC women were in the age group of 26-30 were 32 %. The awareness regarding the various questions like Does HIV transmitted to foetus by mother?- 9 % were Yes, 22 %-No, 69 %-Don’t Know; Do you know tests are there for detection of HIV?- 7 %-Yes, 13 %-No, 80 %-Don’t know; Are you at a risk of Infection?- 4% were Yes, 52% -No, 44 % were Don’t know; Can the disease prevented ? 6 %- Yes, 22 % were No, 72 % were don’t know; Is HIV a Sexually transmitted disease? 33 %-Yes, 22 %-No, 45 %-Don’t know; Can HIV be transmitted by contaminated blood? 32 %-Yes, 20 %-No, 48 %-Don’t know; Can HIV be transmitted by Kissing ?-35 % say Yes, 17 % -No, 48 %-Don’t know; Can HIV be transmitted by sharing food ?- 24 % Yes , 35 %-No, 41 %-Don’t know. From our research, we found that while there is good understanding of the HIV disease, the availability of preventive services through HIV testing is very poor, so subsequent prevention administration drugs are very low, although some myths about the transmission of the disease still remain, such as transmitting through sharing food or transmitting casual hugging or shaking. Conclusion: From our research, it can be concluded that the awareness of the PPTCT services with respect to HIV testing during the ANC era was very low, so that the awareness of it should be increased so that HIV transmission from mother to foetus can be effectively carried out. Key words: HIV testing during pregnancy, PPTCT (Prevention of Parent to Child Transmission)

AIMS & OBJECTIVES:To assess the value of transvaginal Sono hysterosalpingography in evaluating the uterine abnormalities and tubal patency in infertile patients and to compare its results with established methods like hysterosalpingography and laparoscopy. MATERIALS & METHODS:Starting from June 2010, 30 cases of transvaginal Sono hysterosalpingography (SHSG) were carried out on patients of infertility and reproductive wastage. The results of this procedure were compared with HSG in 14 cases and with laparoscopy in 16 cases. In cases where uterine factor was suspected the findings of sonohysterogram were confirmed by office hysteroscopy. RESULTS: Out of the 16 cases confirmed by laparoscopy there was complete agreement with SHSG in 14 (87.5%) cases partial agreement in one (6.25%)and total disagreement in 2 (12.5%) cases out of The 14 cases (85.7%) partial agreement in 1 (7.1%) And total disagreement in 2 cases (14.2%). There was 100% agreement in this findings of sono hysterosalpingography and hysteroscopy. CONCLUSION: There were no false positive cases in SHSG. We than conclude from our study that transvaginal SHSG is a simple & reliable method of evaluating uterine abnormalities and tubal patency its results being comparable to the established methods like HSG and laparoscopy.

Background: Normo-gonadotrophic anovulation is the most prevalent anovulatory infertility type. Polycystic ovary disease (PCOS) is by far the most common cause in this category, accounting for 85 % of females who are anovulatory. Its prevalence is growing increasingly with increasing modernisation. Ovulation induction in PCOS females is a problem and the best drug for ovulation induction is still debatable. Aims & objectives: In the current research, we evaluated the efficacy of clomiphene citrate in infertile women with polycystic ovary disease for ovulation induction and pregnancy rates. Material and Methods: The present research was a prospective study conducted with PCOS, willing to participate and follow up in women with primary/secondary infertility. Rotterdam criteria were used to diagnose PCOS. Using descriptive statistics, statistical analysis was performed. Results: Initially, 140 patients in the current study were recruited. For the current research, 128 patients either born or cared for a full 6 months were considered. 21-25 years of age was the most common age group. The mean age of the patients examined was 26.34 ± 3.6 years. 55 % were having average BMI patients, while 34% were overweight. Primary infertility was present in 77 percent of patients. 73 per cent of patients had infertility duration of 1-5 years. 30 percent have a history of laparoscopic ovarian drilling in patients. In 58 percent, hirsutism was noted. Following serial USG monitoring, mono-follicular development (55 %) was more prevalent than multi-follicular development at the end of the study (45 percent). The mean thickness of the endometrium was 7.78 ± 2.58 mm. The mean days for clomiphene citrate ovulation are 14.84 ± 3.46. Average P4 values on day 21 were 11.48 ± 6.44 ng/ml. At the end of the study, 66 % ovulation rate, 28 % pregnancy rate, and 2 % multiple pregnancy incidence were noted. Conclusion: Ovulation induction with clomiphene citrate should be considered as the first line of treatment for infertile women with PCOS. Initial assessment and careful selection of patients increases pregnancy rates. Keywords: ovulation induction, polycystic ovary disease, clomiphene citrate, pregnancy rate.

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