Intravenous administration of iron sucrose is a safe treatment for correction of anemia in pregnancy, without serious side-effects.

In couples with no other cause of RPL other than a structural chromosomal rearrangement, nearly two-thirds are likely to have a normal outcome in subsequent pregnancy. Couples with pure abortion histories carry higher risk for cytogenetic abnormality than couples with normal children in addition to abortions.

Background High‐frequency 10‐kHz spinal cord stimulation (10‐kHz SCS) has shown promise in multicenter prospective trials for the management of chronic back and leg pain. Traditional spinal cord stimulation (t‐SCS) has a long history of effectiveness in chronic neuropathic syndromes but not uncommonly can fail to provide long‐term relief, leaving a significant group of patients with unsatisfactory outcomes. There is mounting evidence that 10‐kHz SCS may offer relief in this subset of patients. Methods The purpose of this retrospective analysis was to report a single‐institution long‐term experience of 10‐kHz SCS in patients who did not get adequate pain relief with prior t‐SCS devices. A temporary trial of 10‐kHz SCS was carried out for 7 days, and those experiencing an average of 50% reduction in pain intensity underwent implantation. Patients were classified as moderate responders if relief was 31% to 50% and excellent responders if pain relief exceeded 50%. Results Thirty‐one patients who had experienced failed t‐SCS primarily from poor paresthesia coverage underwent a trial of 10‐kHz SCS and 29 underwent implantation. Twenty‐eight patients were available for analysis, with 57.1% experiencing 30% response and 46.4% experiencing excellent response at a median follow‐up of 21.2 (±8.4) months. Conclusions This small single‐institution study suggests that a significant proportion of patients with previously failed t‐SCS may achieve clinically meaningful and durable pain relief with 10‐kHz SCS.