The plant Aloe vera is used in Ayurvedic, Homoeopathic and Allopathic streams of medicine, and not only tribal community but also most of the people for food and medicine. The plant leaves contains numerous vitamins, minerals, enzymes, amino acids, natural sugars and other bioactive compounds with emollient, purgative, antimicrobial, anti inflammatory, anti-oxidant, aphrodisiac, anti-helmenthic, antifungal, antiseptic and cosmetic values for health care. This plant has potential to cure sunburns, burns and minor cuts, and even skin cancer. The external use in cosmetic primarily acts as skin healer and prevents injury of epithelial tissues, cures acne and gives a youthful glow to skin, also acts as extremely powerful laxative.
Aim: The present investigation was undertaken to study the impact of heat stress and hypercapnia on physiological, hematological, and behavioral profile of Tharparkar and Karan Fries (KF) heifers.
Materials and Methods:The animals of both the breeds of Tharparkar and KF were exposed at different temperatures and CO 2 levels. Exposure conditions of 25°C, 400 ppm CO 2 level, and 60% relative humidity (RH) were taken as a control condition. The exposure conditions 40°C with two levels of CO 2 500 ppm and 600 ppm with RH 55±5% and exposure conditions 42°C with two levels of CO 2 500 ppm and 600 ppm with RH 55±5% were taken as treatments. The exposure period in each condition was 4 h daily for 5 consecutive days.
Results: Physiological responses (respiration rate [RR], pulse rate [PR], and rectal temperature [RT]) were significantly (p<0.01) higher and different during all exposure conditions compared to control condition in both the breeds of cattle. KF heifers had higher RR, PR, and RT than Tharparkar heifers. Hematological parameters, namely, red blood cell, hemoglobin, and packed cell volume were significantly higher and different during all exposure condition than control in both the breeds, whereas no significant changes were observed in total leukocyte count and differential leukocyte count. Blood pH increased with increase in temperature and CO 2 levels and was significantly higher than control conditions. PCO 2 and base excess were significantly (p<0.05) lower, and PO 2 was higher during different exposure conditions than control in both breeds. Restlessness and excitement signs were observed in all the exposure conditions as compared to control condition in both the breeds.
Conclusion:Changes in physiological responses, behavioral pattern, and hematological parameters reflect the current functional status of the body system, and it can be used as an index for assessing the adaptation capacity of cattle to predict changes occurring in climate variables due to increasing CO 2 levels and environmental temperature.
This paper provides a detailed overview of the blockchain technology and how it can be used to build a foolproof system in eliminating counterfeit products in pharmaceutical industries. Study by various reports indicate that counterfeit products entering the mainstream supply is by far one of the major issue faced by the pharmaceutical industries. By using blockchain across the whole value chain, various pitfalls and challenges faced by the stakeholders can be resolved as blockchain, by design is (i) robust, (ii) improves transparency, (iii) immutable, (iv) authentic, (v) reliable and (vi) secure. Overall, this paper attempts to provide a roadmap on how blockchain transactions can help various stakeholders improve the counterfeit situation, challenges one might face in implementing a blockchain solution and steps for further research.
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