Background: Anti-Epileptic Drugs (AEDs) are the primary therapeutic modes forepileptic patients and have been demonstrated to control seizure, which decreasesmorbidity and mortality associated with epilepsy. There is a paucity of data on drugadherence and seizure control status among epileptic patients in Bangladesh. Theaim of this study was therefore to assess adherence among epileptic patients and tosee association between adherence and control of seizures. Methods and materials: A cross-sectional observational study was conductedamong 253 patients who visited into outdoor and admitted inindoor of Neurologyand Medicine Department of Chattogram Medical College Hospital (CMCH) with aclinical diagnosis of epilepsy. Epileptic Patients who had taken AED for at least oneyear or more were recruited in the study to evaluate adherence and seizure controlthrough patient interview. Factors affecting adherence were determined usingregression analysis. Results: 38.8% patients were adherent to their treatment and only 33.6% of thepatients had controlled seizure, forgetfulness (35%) was the most reason for nonadherence.Monontherapy was commonly (72.7%) used, among which Valproic acidwas the most commonly utilized (30.4%) single anticonvulsant drug. Many factorswere affecting patient’s adherence such as socio-demographic related factors (age,education, occupation), therapy related factors and cost. Adherence to AED wasfound to have a significant association with seizure control status. Conclusions: The rate of adherence observed in this study was low. The mostcommon reason for nonadherence was forgetfulness. The findings indicate thatadherence was associated with well seizure control. Chatt Maa Shi Hosp Med Coll J; Vol.19 (1); January 2020; Page 68-73

Dyke-Davidoff-Masson Syndrome (DDMS), also known as cerebral hemiatrophy, is a rare clinical condition characterized by seizures, facial asymmetry, contralateral spastic hemiplegia or hemiparesis, with learning difficulties and behavioral changes. It is commonly diagnosed in presence of clinical feature associated radiological findings which include cerebral hemiatrophy with homolateral hypertrophy of the skull and sinuses. In this present case report a 12 year old teenager female patient was diagnosed as DDMS with recurrent generalized seizures, learning difficulties and right sided hemiparesis. Magnetic resonance imaging (MRI) of the brain showed hemiatrophy involving the left cerebral hemisphere and EEG showed generalized epileptiform discharged. An X-ray of the paranasal air sinuses was normal. [J Shaheed Suhrawardy Med Coll, 2013;5(2):111-113]

Background: A high proportion of patients suffering from an acute stressful condition asuch as stroke or myocardial infarction may develop hyperglycemia even in the absence of a preexisting diagnosis of diabetes. The study evaluates the effect of hyperglycemia in the severity and outcome during the acute phase of stroke. Methods: This was a descriptive cross-sectional study. Baseline variables (eg: age, sex, smoking, hypertension, diabetes OHA/insulin) and outcome measures (mortaily, disability) were statistically analysed and compared with a control group of 50 patients of acute ischemic storke without admission hyperglycemia. Result: the base line characteristis of the two patient groups were comparable. The 1st week mortality was 16% in case group and 2% in the control group. the 30 days mortality in the case group and control group was 28% and 12% respectively, 58.33% were disabled & dependent in the hyperglycemia group, in comparison to 36.36% subjects in the control group. Conclusion: Admission hyperglycemia seems worsen the outcome and functional disability during the acute phase of Ischemic stroke. Admission glucose level is an important risk factor and should be immediately treated to reduce morbitidity & mortality in acute Ischemic stroke cases Bangladesh Journal of Neuroscience 2016; Vol. 32 (1): 28-33

Background: Idiopathic facial paralysis is one of the commonest conditions in neurological practice. Objective: The purpose of this study is to see whether Bell’s palsy is associated with serological marker of Herpes Simplex virus type 1, and to study the clinical signs and symptoms manifested by Bell’s palsy. Methodology: This retrospective observational study was carried out in neurology OPD of ShSMCH, Dhaka from June, 2014 to May, 2016. All the patients who came to the OPD were selected as study population. All relevant data, those who fulfill the inclusion criteria were recorded in pre-designed data collection sheet. Result: A total number of 60 were recruited in this study. 30 were case group and 30 were control group. In our study, more than one quarter of cases (26.7%) was found between 26-30 years, while lowest age incidence was 16-20 years (6.7%). More than 37% of cases had their attack of Bell’s palsy in monsoon season, only 3% in autumn. 52.3% had pain in or around the ear. Taste abnormalities were found in 23.3%. Conclusion: From this study, it can be concluded that, Herpes simplex type 1 may be an important causative agent for Bell’s palsy. But a large scale study is needed for establishment of Herpes Simplex type 1 as an important infective agent for causation of Bell’s palsy. Bangladesh Journal of Neuroscience 2016; Vol. 32 (1): 12-15

We carried out case control study aimed to evaluate abdominal obesity as a risk factor for ischemic stroke. Though it became established as a risk factor for cardiovascular disease, still its association with stroke is less clear. We have taken ninety cases with ischemic stroke and compare waist to hip ratio & waist circumference with same numbers of age and sex matched stroke free people as controls. There are standard markers of abdominal obesity & their cut-off values and ways of measurement were taken from International Diabetic Federation. Both increase waist to hip ratio (63.3% in cases & 26.7% in controls) and increase waist circumference (66.7% in cases & 25.6% in controls) were significant (P<.05) and showed marked strength of association (odds ratio >1) in ischemic stroke patients. After adjusting the significant risk factors in all age and sex matched cases and controls by conditional logistic regression analysis, WHR and WC still showed significant strength of association with ischemic stroke in all groups. The increase abdominal obesity markers were found to have greater association in both female and male cases in relation to their control counterparts. So, in the light of current study we may suggest that abdominal obesity defined as increase waist circumference and waist to hip ratio attribute considerably to the estimate of ischemic stroke events. Bangladesh Journal of Neuroscience 2011; Vol. 27 (2) : 69-73 DOI: http://dx.doi.org/10.3329/bjn.v27i2.17545