This paper presents an approach to segment lesions from brain magnetic resonance images in a fully automatic manner. The proposed idea leverages the strength of classical random walker algorithm and graph cut optimization technique in a single framework. We demonstrate that formulating a "prior" from a stochastic model can ameliorate the need of manually selected seed selection process in the random walker framework, thus making the algorithm fully automatic in a generic manner. By analytically solving a linear system of equations in the random walk process, initial labelling ∈ [0, 1] of each pixel in the image are computed to obtain the likelihood probability. These probabilities are then used to compute the likelihood for the data fidelity term in the energy function to compute the final segmentation, which is minimized by min cut max flow algorithm. Experimental results show the superiority of the proposed method over the state-of-the-art techniques on publicly available datasets. Recently there has been tremendous progress in MR image segmentation algorithms. A large body of literature has been reported in this area in the last two decades [4, 5]. However, This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
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