Tetralogy of Fallot is the most common cyanotic congenital heart disease. Corrective surgery is indicated during infancy for the best outcome, however, due to poor availability and affordability of surgery, many children of resource-poor settings live with uncorrected tetralogy of Fallot. They suffer from dreaded complications like brain abscess, in later years of life. We report 3 cases of tetralogy of Fallot who developed brain abscess during their childhood.