Kasus IMS yang terus meningkat merupakan salah satu penyebab utama dari buruknya kesehatan sebuah negara dan dunia dan Kota Mataram merupakan ibu kota Provinsi NTB, salah satu destinasi wisata yang banyak diminati oleh wisatawan. Hal ini menimbulkan dampak positif maupun negatif. Dampak positifnya, banyaknya wisatawan berkunjung untuk berlibur dan meningkatkan roda perekonomian. Namun dampak negatif yang terjadi, berhubungan dengan kedatangan wisatawan yang kemudian memanfaatkan tempat-tempat hiburan dan secara tidak langsung berkaitan dengan peningkatan aktifitas seksual. Tujuan Penelitian untuk mengetahui gambaran Patogen dan Profil Infeksi Menular Seksual (IMS) di 10 Puskesmas se Kota Mataram Provinsi Nusa Tenggara Barat Tahun 2015-2019. Jenis penelitian ini adalah penelitian deskriptif dengan pendekatan retrospektif dengan mengambil data dari catatan rekam medis pasien di seluruh puskesmas di Kota Mataram, dengan total 2.340 orang yang terinfeksi, dan teknik sampling menggunakan teknik total sampling. Berdasarkan hasil penelitian, penyaki infeksi menular seksual di seluruh puskesmas di kota Mataram, Nusa Tenggara Barat sejak tahun 2015-2019 di dominasi oleh jenis kelamin perempuan, usia dewasa awal, sudah menikah, SMP, tidak bekerja, kelompok risiko pasangan risti. Hasil dari data kasus IMS yang di laporkan di Kota Mataram sejak tahun 2015-2019 cenderung disebabkan oleh bakteri.
BACKGROUND: BauNyale festival is a Lombok tradition that originated in the Kuta beach tourism area in Central Lombok. The locals of Lombok Island gathered in this location to harvest marine worms known as Nyale (Eunice sp.). The ability of marine worms to act as anticancer agents has received little attention in Indonesia. AIM: This study aimed to examine the biomolecules compounds of Nyale as antimitotic candidates. METHODS: This was a preliminary study using post-test only with a control group design. The sample of this study was Nyale (Eunice sp.), and sea urchin (Tripneustes ventricosus) collected from Kuta beach, Central Lombok. The Nyale was extracted with 96% ethanol as the solvent. Gas Chromatography-Mass Spectrometry (GCMS) was used to determine the content of bioactive compounds. Sea urchin embryos were divided into four treatment groups (control; 10 mg, 100 mg, and 1000 mg; 1000 mg of Nyale extract). After 2 h of fertilization incubation, the number of cell division phases (2–32 cells) was counted. The data were analyzed using ANOVA. RESULTS: The results of the GCMS test revealed that there were ten different compounds in the Nyale ethanol extract. There was a tendency for cleavage when testing the anti-mitotic potential of Nyale extract in each group. There was a significant difference in the percentage of cell changes in all treatments (control, 10 mg, 100 mg, and 1000 mg) (p < 0.005). CONCLUSION: Bioactive compounds found in marine worms (nyale) influence the percentage of cell division (anti-mitotic) in sea urchin embryos.
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